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Following the povorcitinib/povo Phase3 results in moderate to severe hidradenitis suppurativa, HS, the firm believes that the data were statistically significant but missed expectations on magnitude of benefit, adding that it sees povo as “modestly competitive”, the analyst tells investors in a research note. The firm adds that its updated model reflects povo as a second-line opportunity in HS with peak sales of $550M vs. $900M consensus.Discover stocks' market position with detailed  competitor analyses.Read More on INCY:Questions or Comments about the article?Incyte’s Stock Downgraded to Sell Amid Disappointing Drug Data and Market Challenges. Guggenheim downgrades Incyte on povorcitinib’s ‘somewhat underwhelming’ profile. Incyte downgraded to Market Perform from Outperform at William Blair. Incyte downgraded to Neutral from Buy at Guggenheim. Incyte’s Promising Phase 3 Results an","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/incyte-price-target-lowered-72-120610950.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/incyte-price-target-lowered-72-120610950.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["INCY"],"gpt_icon":0},{"id":"2520932171","title":"Incyte Corp. Stock Slips 3.2%, Underperforms Market","url":"https://stock-news.laohu8.com/highlight/detail?id=2520932171","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520932171?lang=en_us&edition=fundamental","pubTime":"2025-03-19 04:35","pubTimestamp":1742330100,"startTime":"0","endTime":"0","summary":"This article was automatically generated by Dow Jones using technology from Automated Insights.Shares of Incyte Corp. shed 3.2% to $60.00 on what proved to be an all-around dismal trading session for the stock market, with the S&P 500 Index falling 1.1% to 5,614.66 and Dow Jones Industrial Average falling 0.6% to 41,581.31.This was the stock's second consecutive day of losses.Incyte Corp. closed 28.5% short of its 52-week high of $83.95, which the company reached on November 8th.The stock demonstrated a mixed performance when compared to some of its competitors, as Alnylam Pharmaceuticals Inc. fell 3.5% to $244.30, Bio-Techne Corp. rose 0.4% to $62.83, and BioMarin Pharmaceutical Inc. remained unchanged.Trading volume totaled 3.3 million, compared to the 50-day average of 1.7 million.","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["INCY"],"gpt_icon":0},{"id":"2520089932","title":"INCY Stock Down on Disappointing Skin Disease Study Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2520089932","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520089932?lang=en_us&edition=fundamental","pubTime":"2025-03-19 03:00","pubTimestamp":1742324400,"startTime":"0","endTime":"0","summary":"Shares of Incyte INCY were down 8.62% on Monday after the announcement of data from two late-stage studies on an oral small-molecule JAK1 inhibitor, povorcitinib, for the treatment of hidradenitis suppurativa .HS, a chronic inflammatory skin condition, is characterized by painful nodules and abscesses.While both the late studies STOP-HS1 and STOP-HS2 studies met their primary endpoint, the results lagged investor expectations, and consequently, shares declined.Povorcitinib is an oral small-molecule JAK1 selective inhibitor currently in phase III studies for HS, vitiligo and prurigo nodularis , as well as phase II trials for asthma and chronic spontaneous urticaria .The phase III studies STOP-HS1  and STOP-HS2  are evaluating the efficacy and safety of povorcitinib in adult patients with moderate to severe HS. Both studies include a 12-week double-blind, placebo-controlled treatment period, followed by a 42-week extension period and 30-day safety follow-up.Data from the STOP-HS2 study s","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/incy-stock-down-disappointing-skin-190000520.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4583","BK4588","BK4139","IE0002270589.USD","IE00BZ1G4Q59.USD","BMRN","INCY","IE00B7SZLL34.SGD","LU1585245621.USD","LU1839511570.USD","GSK.UK","BK4578","LU0320765992.SGD","BK4550","LU1169589451.USD","QD","BK4585","BK4532","GILD","LU0889565916.HKD","LU2087621335.USD","BK4566","BK4007","BK4166","LU0109394709.USD","LU1066051498.USD","LU1430594728.SGD","LU0289739699.SGD","IE00BKVL7J92.USD","IE00BSNM7G36.USD","BK4563","AN","BK4214","BK4568","LU2468319806.SGD","LU1169590202.USD","LU1829250122.USD","IE00B3T34201.USD","LU2089984988.USD","LU0058720904.USD","IE00B19Z3581.USD","LU1066053197.SGD","LU1571399168.USD","GSK","PN","BK4503","IE00B19Z3B42.SGD","LU0234570918.USD"],"gpt_icon":0},{"id":"2520846639","title":"Incyte’s Povorcitinib Shows Promise but Faces Competitive and Market Challenges, Leading to Hold Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2520846639","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520846639?lang=en_us&edition=fundamental","pubTime":"2025-03-19 01:35","pubTimestamp":1742319311,"startTime":"0","endTime":"0","summary":"JMP Securities analyst Reni Benjamin has reiterated their neutral stance on INCY stock, giving a Hold rating today. Reni Benjamin has given his Hol...","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/incytes-povorcitinib-shows-promise-but-faces-competitive-and-market-challenges-leading-to-hold-rating?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/incytes-povorcitinib-shows-promise-but-faces-competitive-and-market-challenges-leading-to-hold-rating?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["INCY"],"gpt_icon":0},{"id":"2520262819","title":"Incyte Corporation  : Deutsche Bank Cuts Target Price to $60 From $70","url":"https://stock-news.laohu8.com/highlight/detail?id=2520262819","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520262819?lang=en_us&edition=fundamental","pubTime":"2025-03-18 18:58","pubTimestamp":1742295486,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250318:nAQN2K65P9:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4550","BK4139","INCY","BK4588","BK4532","BK4585"],"gpt_icon":0},{"id":"2520664081","title":"Guggenheim Downgrades Incyte to Neutral From Buy","url":"https://stock-news.laohu8.com/highlight/detail?id=2520664081","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520664081?lang=en_us&edition=fundamental","pubTime":"2025-03-18 18:40","pubTimestamp":1742294438,"startTime":"0","endTime":"0","summary":"Incyte (INCY) has an average rating of overweight and mean price target of $75.84, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research from major banks","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["INCY"],"gpt_icon":0},{"id":"2520428640","title":"Incyte downgraded to Market Perform from Outperform at William Blair","url":"https://stock-news.laohu8.com/highlight/detail?id=2520428640","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520428640?lang=en_us&edition=fundamental","pubTime":"2025-03-18 18:36","pubTimestamp":1742294166,"startTime":"0","endTime":"0","summary":"William Blair downgraded Incyte (INCY) to Market Perform from Outperform. 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In this article, we are going to take a look at where Incyte Corporation  stands against other best biotech stocks.Although biotech stocks had a “challenging” year in 2024, JPMorgan believes that some of the industry’s companies could see significant growth in the months to come. Senior partner and principal of investments at Novo Holdings, Johan Hueffer, spoke on CNBC on November 28 about his macro outlook for life sciences investments. He claimed that in the past few years, biotechs have had trouble raising funding. Over the past quarter or two, though, that tendency has begun to improve.Flood’s report also emphasized how the biotech sector has recently demonstrated better fundamentals, which have been ascribed to superior clinical outcomes and a more favorable regulatory environment. Goldman’s data shows that hedge funds continue to underinvest in biotechnology despite these tailwinds. 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The...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/blurbs/td-cowen-reaffirms-their-buy-rating-on-incyte-incy-4?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/blurbs/td-cowen-reaffirms-their-buy-rating-on-incyte-incy-4?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["COWN","INCY","TD"],"gpt_icon":0},{"id":"2520859336","title":"Incyte Corp. 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