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Johnson's Investigational Colitis Treatment Meets Primary Endpoint in Phase 2b Trial","url":"https://stock-news.laohu8.com/highlight/detail?id=2518225421","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518225421?lang=en_us&edition=fundamental","pubTime":"2025-03-10 20:35","pubTimestamp":1741610122,"startTime":"0","endTime":"0","summary":"Johnson & Johnson  said Monday that its potential ulcerative colitis treatment icotrokinra met the primary endpoint of clinical response in all dosages in a 252-patient phase 2b study.The investigational drug also showed \"clinically meaningful\" differences versus placebo in secondary endpoints of clinical remission, symptomatic remission, and endoscopic improvement at week 12, the company said.Icotrokinra at the highest doses showed a response rate of 63.5% for patients with chronic large intestine disease after 12 weeks, versus 27% for placebo, and a remission rate of 30.2%, versus 11.1% for the placebo, the company said.It added that remission and response rates continued to improve through week 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Canada Authorizes Lazcluze® (Lazertinib) in Combination With Rybrevant® (Amivantamab) as a First-Line Chemotherapy-Free Treatment for Patients With Egfr-Mutated Advanced Lung Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2518256772","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518256772?lang=en_us&edition=fundamental","pubTime":"2025-03-10 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Canada authorizes LAZCLUZE® (lazertinib) in combination with RYBREVANT® (amivantamab) as a first-line chemotherapy-free treatment for patients with EGFR-mutated advanced lung cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2518226306","media":"CNW Group","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518226306?lang=en_us&edition=fundamental","pubTime":"2025-03-10 20:30","pubTimestamp":1741609800,"startTime":"0","endTime":"0","summary":"Phase 3 MARIPOSA study showedLAZCLUZE plus RYBREVANT significantly improved progression-free survival, reducing the risk of disease progression or death by 30 per cent versus osimertinib alone.1. TORONTO, March 10, 2025 /CNW/ - Johnson & Johnson  announced today that Health Canada has issued a Notice of Compliance  for LAZCLUZE  in combination with RYBREVANT  for the first-line treatment of adult patients with locally advanced or metastatic non-small cell lung cancer  with epidermal growth factor receptor  exon 19 deletions or exon 21 L858R substitution mutations.1 Janssen Inc., a Johnson & Johnson company, is the market authorization holder for LAZCLUZE  and RYBREVANT in Canada.\"Each breakthrough in the treatment of lung cancer provides new hope for patients,\" says Shem Singh***, Executive Director of Lung Cancer Canada. \"Findings from the MARIPOSA study show new progress in the treatment of NSCLC with EGFR mutations, including a meaningful increase in progression-free survival. The a","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/health-canada-authorizes-lazcluze-lazertinib-123000098.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0203345920.USD","LU1032466523.USD","LU0640476718.USD","LU1032955483.USD","BK4564","IE00BJJMRZ35.SGD","LU0122379950.USD","BK4187","JNJ","IE00B3PB1722.GBP","LU0345770308.USD","LU1261432733.SGD","SG9999002224.SGD","LU1988902786.USD","LU1066051225.USD","IE00B4R5TH58.HKD","LU1674673691.USD","IE00B2B36J28.USD","LU2129689431.USD","LU0792757196.USD","LU1221951129.SGD","LU1066051811.HKD","BK4585","LU1061106388.HKD","LU0345770993.USD","BK4534","BK4504","IE00B42XCP33.USD","LU1244550577.SGD","LU1778281490.HKD","LU2129689514.USD","NOC","LU0289739699.SGD","LU2264538146.SGD","LU0234570918.USD","LU2133065610.SGD","LU2430703095.HKD","IE0009355771.USD","LU1506573853.SGD","SG9999002232.USD","BK4603","IE00BDGV0183.EUR","IE00B7SZLL34.SGD","LU0912757837.SGD","PFS","LU1914381329.SGD","LU1066053197.SGD","LU1585245621.USD","BK4533","IE0002270589.USD"],"gpt_icon":0},{"id":"2518226539","title":"Protagonist Reports Positive Top Line Results From Phase 2b Study of Icotrokinra Showing Potential to Transform the Treatment Paradigm for Patients With Ulcerative Colitis","url":"https://stock-news.laohu8.com/highlight/detail?id=2518226539","media":"ACCESS Newswire","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518226539?lang=en_us&edition=fundamental","pubTime":"2025-03-10 20:15","pubTimestamp":1741608900,"startTime":"0","endTime":"0","summary":"Clinical response rate of 63.5% and clinical remission rate of 30.2% achieved at Week 12 with the highest dose, which continued to improve through Week 28. All three doses met the primary endpoint of clinical response at Week 12, with a favorable safety profile. These results in ulcerative colitis build on strong data recently reported for the plaque psoriasis Phase 3 program. NEWARK, CALIFORNIA / ACCESS Newswire / March 10, 2025 / Protagonist Therapeutics, Inc.  today announced positive topline results from ANTHEM-UC, a Phase 2b study of icotrokinra , the first investigational targeted oral peptide that selectively blocks the IL-23 receptor, in adults with moderately to severely active ulcerative colitis . The study conducted by Protagonist's collaboration partner, Johnson & Johnson, met its primary endpoint of clinical responsea in all icotrokinra dose groups evaluated. Additionally, the study demonstrated clinically meaningful differences versus placebo in key secondary endpoints 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meets primary endpoint of clinical response in ulcerative colitis study and shows potential to transform the treatment paradigm for patients","url":"https://stock-news.laohu8.com/highlight/detail?id=2518223792","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518223792?lang=en_us&edition=fundamental","pubTime":"2025-03-10 20:00","pubTimestamp":1741608000,"startTime":"0","endTime":"0","summary":"Clinical response and remission rates continued to improve through Week 28, building on strong data recently reported for the plaque psoriasis Phase 3 program. Icotrokinra demonstrates potential to offer therapeutic benefit and tolerability with a once daily oral treatment. SPRING HOUSE, Pa., March 10, 2025 /PRNewswire/ -- Johnson & Johnson today announced positive topline results from ANTHEM-UC, a Phase 2b study of icotrokinra , the first investigational targeted oral peptide that selectively blocks the IL-23 receptor, in adults with moderately to severely active ulcerative colitis . The study met its primary endpoint of clinical responsea in all icotrokinra dose groups evaluated and demonstrated clinically meaningful differences versus placebo in key secondary endpoints of clinical remissionb, symptomatic remission and endoscopic improvement at Week 12.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/icotrokinra-meets-primary-endpoint-clinical-120000377.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/icotrokinra-meets-primary-endpoint-clinical-120000377.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2468319806.SGD","IE00BVYPNW00.USD","IE00B19Z3B42.SGD","IE00B7SZLL34.SGD","LU1280957306.USD","LU2430703251.USD","IE00B4R5TH58.HKD","LU1221951046.USD","LU0289739699.SGD","LU1032466523.USD","BK4559","LU0345770308.USD","LU0640476718.USD","LU1674673691.USD","LU1718418525.SGD","IE00BJJMRZ35.SGD","LU0792757196.USD","LU1162221912.USD","LU2505996681.GBP","LU1061106388.HKD","LU1244550494.USD","LU0098860793.USD","LU1914381329.SGD","LU1935042991.SGD","LU0320765646.SGD","LU0345770993.USD","LU2430703178.SGD","LU1674673428.USD","LU1778281490.HKD","LU2430703095.HKD","BK4532","LU1506573853.SGD","IE0034235303.USD","IE000M9KFDE8.USD","JNJ","LU0122379950.USD","LU1196500208.SGD","BK4568","LU1244550577.SGD","LU0345769631.USD","LU2133065610.SGD","IE0002141913.USD","IE0009355771.USD","BK4504","LU1261432733.SGD","LU2347655156.SGD","LU1221951129.SGD","LU0203345920.USD","BK4534","LU1430594728.SGD"],"gpt_icon":0},{"id":"2518322144","title":"Take the Zacks Approach to Beat the Markets: NioCorp, AngloGold, Amgen in Focus","url":"https://stock-news.laohu8.com/highlight/detail?id=2518322144","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518322144?lang=en_us&edition=fundamental","pubTime":"2025-03-10 18:35","pubTimestamp":1741602900,"startTime":"0","endTime":"0","summary":"The three most widely followed U.S. indexes ended in red last week. The S&P 500, the Dow Jones Industrial Average and the Nasdaq Composite slid 1.36%, 0.90% and 0.84%, respectively. The aggressive shifting of U.S. policies and foreign trade tariffs with major trading partnersunder President DonaldTrump’s new administration has compelled investors to rethink their strategies. Concerns also surfaced over a slowdown in economic growth and rise in inflation due to the new government policies.Personal consumption expenditure , the Fed’s preferred inflation gauge, increased by 0.3% in January, higher than the Federal Reserve’s 2% target, and showed a 2.5% annual rate. The disproportion between the rise in personal income by 0.9% and the unexpected decline in personal spending by 0.2% in January indicates that average Americans are concerned about future economic conditions. Retail sales and building construction decreased last month. Also, consumer sentiment and consumer confidence indexes f","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/zacks-approach-beat-markets-niocorp-103500611.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2237443895.HKD","LU1032955483.USD","SG9999015986.USD","SPXU","AMGN","LU0264606111.USD","VOO","LU0345770993.USD","LU0098860793.USD",".SPX","LU0516422440.USD","LU0154236417.USD","OEX","PRMB","LU0689626769.HKD","SSO","LU1571399168.USD","FOX","KO","AZO","LU1037948541.HKD","TXO","LU2125154935.USD","SDS","IE0034224299.USD","LU2129689514.USD","BK4536","SG9999004360.SGD","AU","IE00BLSP4239.USD","LU1670711040.USD","LU1261432733.SGD","FDN","LU0130102774.USD","ECDP","NB","UBER","ESmain","JNJ","OEF","LU1242518857.USD","UPRO","IE0002141913.USD","IVV","SG9999002224.SGD","ICE","SPY","SH","NOBL"],"gpt_icon":1},{"id":"2518862404","title":"3 ETFs to Buy Now for Passive Dividend Income","url":"https://stock-news.laohu8.com/highlight/detail?id=2518862404","media":"Motley Fool","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518862404?lang=en_us&edition=fundamental","pubTime":"2025-03-09 18:15","pubTimestamp":1741515300,"startTime":"0","endTime":"0","summary":"The Schwab U.S. Dividend Equity ETF provides exposure to various sectors without charging high management fees.The Vanguard Dividend Appreciation ETF provides passive income without compromising on growth.The Vanguard Total Corporate Bond ETF is a relatively safe way to earn some income and invest in corporate bonds.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.fool.com/investing/2025/03/09/3-etfs-to-buy-now-for-passive-dividend-income/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"fool_stock","symbols":[".IXIC","SH","QID","AMGN","FDN","US12M.BOND","USAW.SI","NVIW.SI","UPRO","NQmain","ESmain","US5Y.BOND","XOM","US30Y.BOND","ABBV","MACW.SI","OEF","CSCO",".SPX","PG","VOO","US7Y.BOND","JNJ","PSQ","US10Y.BOND","US6M.BOND","US2Y.BOND","USJW.SI","SDS","SPY","TQQQ","MA","TSYW.SI","HD","SQQQ","IVV","MNQmain","US3Y.BOND","OEX","QLD"],"gpt_icon":1},{"id":"2517441983","title":"BRIEF-J&J Says Phase 3 Iconic-Advance 1&2 Studies Met Their Co-Primary Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2517441983","media":"Reuters","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517441983?lang=en_us&edition=fundamental","pubTime":"2025-03-08 22:07","pubTimestamp":1741442877,"startTime":"0","endTime":"0","summary":"BRIEF-J&J Says Phase 3 Iconic-Advance 1&2 Studies Met Their Co-Primary EndpointsMarch 8 (Reuters) - Johnson & Johnson JNJ.N:J&J - ICOTROKINRA RESULTS SHOW POTENTIAL TO SET A NEW STANDARD OF TREATMENT ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250308:nFWN3PR08D:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU1162221912.USD","BK4592","IE00B3PB1722.GBP","LU2347655156.SGD","LU1935042991.SGD","BK4007","LU0234572021.USD","LU1221951046.USD","LU2430703178.SGD","LU2468319806.SGD","BK4559","SG9999002232.USD","LU2129689431.USD","LU0889566641.SGD","LU0122379950.USD","IE00B7SZLL34.SGD","IE00BFTCPJ56.SGD","JNJ","LU1267930813.SGD","IE00B1BXHZ80.USD","IE00BDGV0183.EUR","IE00B2B36J28.USD","LU2089984988.USD","LU2505996681.GBP","LU1057294990.SGD","LU2505996509.AUD","IE00BSNM7G36.USD","IE00B19Z3B42.SGD","LU0466842654.USD","BK4585","LU0345769128.USD","LU1032955483.USD","LU2133065610.SGD","LU0320765646.SGD","BK4504","SG9999002224.SGD","LU0058720904.USD","LU1585245621.USD","LU1196500208.SGD","IE0034235303.USD","LU2129689605.HKD","LU0098860793.USD","IE0002141913.USD","IE00B42XCP33.USD","LU1061106388.HKD","LU1066051498.USD","LU1894683264.USD","LU1718418525.SGD","SG9999001440.SGD","LU2112291526.USD"],"gpt_icon":0},{"id":"2517444168","title":"J&J - Icotrokinra Results Show Potential to Set a New Standard of Treatment in Plaque Psoriasis","url":"https://stock-news.laohu8.com/highlight/detail?id=2517444168","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517444168?lang=en_us&edition=fundamental","pubTime":"2025-03-08 22:04","pubTimestamp":1741442646,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250308:nFWN3PR08D:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["IE00B4R5TH58.HKD","LU2505996509.AUD","LU2129689514.USD","IE00BJJMRZ35.SGD","LU1066051225.USD","BK4532","IE00BVYPNW00.USD","LU0058720904.USD","LU2089984988.USD","LU2430703251.USD","IE00B7SZLL34.SGD","LU0098860793.USD","BK4550","LU1221951046.USD","LU0203347892.USD","LU1674673428.USD","IE0009355771.USD","IE00BVYPNV92.GBP","LU1057294990.SGD","LU0203345920.USD","SG9999002232.USD","BK4504","LU1732799900.SGD","LU1929549753.HKD","LU1032955483.USD","LU0345770993.USD","IE00BFTCPJ56.SGD","SG9999002224.SGD","IE0002270589.USD","BK4568","LU0795875169.SGD","LU1244550221.USD","LU2430703095.HKD","LU1778281490.HKD","BK4581","LU0640476718.USD","IE00B19Z3B42.SGD","LU0466842654.USD","LU0234572021.USD","IE000M9KFDE8.USD","LU1732800096.USD","LU1074936037.SGD","LU0122379950.USD","LU1585245621.USD","BK4559","LU1244550494.USD","BK4588","JNJ","LU2112291526.USD","IE00B19Z3581.USD"],"gpt_icon":0},{"id":"2517441682","title":"J&J - Phase 3 Iconic-Advance 1&2(E )Studies Met Their Co-Primary Endpoints","url":"https://stock-news.laohu8.com/highlight/detail?id=2517441682","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517441682?lang=en_us&edition=fundamental","pubTime":"2025-03-08 22:04","pubTimestamp":1741442646,"startTime":"0","endTime":"0","summary":null,"market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250308:nFWN3PR08D:2","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["BK4550","LU1732799900.SGD","BK4559","BK4581","LU2430703095.HKD","BK4588","IE00BVYPNW00.USD","LU0466842654.USD","LU0203347892.USD","LU1066051225.USD","LU1244550494.USD","LU0058720904.USD","LU1221951046.USD","LU0795875169.SGD","LU1929549753.HKD","IE00B7SZLL34.SGD","LU1732800096.USD","LU1674673428.USD","LU0234572021.USD","IE00BFTCPJ56.SGD","LU0345770993.USD","LU2129689514.USD","LU2089984988.USD","JNJ","IE00B19Z3B42.SGD","IE0002270589.USD","IE00BVYPNV92.GBP","LU1074936037.SGD","LU1778281490.HKD","IE00B19Z3581.USD","IE00B4R5TH58.HKD","BK4532","LU1244550221.USD","BK4504","BK4568","LU1585245621.USD","LU2505996509.AUD","LU2112291526.USD","LU0640476718.USD","SG9999002224.SGD","LU0098860793.USD","LU0122379950.USD","LU1057294990.SGD","LU2430703251.USD","SG9999002232.USD","IE000M9KFDE8.USD","IE0009355771.USD","IE00BJJMRZ35.SGD","LU0203345920.USD","LU1032955483.USD"],"gpt_icon":0},{"id":"2517441022","title":"Icotrokinra results show potential to set a new standard of treatment in plaque psoriasis","url":"https://stock-news.laohu8.com/highlight/detail?id=2517441022","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517441022?lang=en_us&edition=fundamental","pubTime":"2025-03-08 22:00","pubTimestamp":1741442400,"startTime":"0","endTime":"0","summary":"Standout combination of complete skin clearance and favorable safety profile in a once daily pill could shift treatment paradigm. Nearly half of patients with moderate-to-severe plaque psoriasis  treated with investigational icotrokinra achieved completely clear skin  at Week 24 in Phase 3 ICONIC-LEAD. Topline results from Phase 3 ICONIC-ADVANCE 1&2studies show icotrokinra achieved co-primary endpoints and showed superiority to deucravacitinib in moderate-to-severe plaque PsO. Data from the Phase 3 ICONIC-LEADa study, presented as a late-breaking abstract at the 2025 American Academy of Dermatology  Annual Meeting, show once daily icotrokinra demonstrated significant skin clearance and a favorable safety profile in adults and adolescents 12 years of age and older with moderate-to-severe plaque PsO.1. \"People living with moderate-to-severe plaque psoriasis are seeking options that balance efficacy, safety and ease of use,\" said Robert Bissonnette, M.D., Chairman at Innovaderm Research, ","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/icotrokinra-results-show-potential-set-140000829.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/icotrokinra-results-show-potential-set-140000829.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BSNM7G36.USD","LU1732799900.SGD","LU1221951046.USD","LU0203347892.USD","LU1244550577.SGD","BK4568","IE000M9KFDE8.USD","LU0114720955.EUR","LU1894683348.USD","LU2112291526.USD","JNJ","BK4585","IE00BDGV0183.EUR","LU1162221912.USD","LU1074936037.SGD","LU1778281490.HKD","LU0345770993.USD","IE0002270589.USD","RCT","LU0122379950.USD","LU0882574055.USD","LU0345769631.USD","IGA","LU2468319806.SGD","LU1585245621.USD","LU0889566641.SGD","BK4581","BK4534","BK4588","LU1506573853.SGD","BK4559","BK4550","LU0203345920.USD","LU1261432733.SGD","IE00B19Z3581.USD","LU0912757837.SGD","LU1066051225.USD","LU0234570918.USD","LU1280957306.USD","LU2602419157.SGD","LU0795875169.SGD","LU1023059063.AUD","LU2089984988.USD","IE00B19Z3B42.SGD","IE00B1BXHZ80.USD","LU1066051811.HKD","SG9999001440.SGD","BK4533","LU0640476718.USD"],"gpt_icon":0},{"id":"2517464657","title":"Buy Gilead Sciences (GILD) Stock at 52-Week Highs?","url":"https://stock-news.laohu8.com/highlight/detail?id=2517464657","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517464657?lang=en_us&edition=fundamental","pubTime":"2025-03-08 04:54","pubTimestamp":1741380840,"startTime":"0","endTime":"0","summary":"Medical pioneer Gilead Sciences GILDhas seen its stock etch out new 52-week highs as the broader market pulled back sharply in recent weeks. Gilead has joined Johnson & Johnson JNJ, and a cluster of healthcare stocks that have risen to fresh peaks.This makes it a worthy topic of whether Gilead’s stock can reach higher highs with investors scoping out exposure to the medical sector amid economic uncertainty. Trading at $117 a share, GILD has spiked nearly +30% year to date with the broader market indexes in negative territory.Bringing in $28.75 billion in 2024, Gilead’s top line is expected to dip 1% this year but is projected to rebound and rise 4% in fiscal 2026 to $29.7 billion.More intriguing, Gilead’s operational efficiency has led the company and its stock back to prominence. Gilead’s annual earnings are expected to soar 70% in FY25 to $7.87 per share compared to EPS of $4.62 last year. Plus, FY26 EPS is projected to increase another 5%.Gilead Sciences, Inc.  : Free Stock Analysis","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/buy-gilead-sciences-gild-stock-205400778.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4534","BK4139","LU0792757196.USD","LU0234570918.USD","LU1430594728.SGD","BK4007","LU0234572021.USD","LU1674673428.USD","BK4588","BK4559","SG9999002232.USD","GILD","LU1894683348.USD","LU0122379950.USD","IE00B7SZLL34.SGD","JNJ","LU2089984988.USD","LU2505996681.GBP","IE00BDGV0183.EUR","LU1914381329.SGD","LU1929549753.HKD","BK4583","LU1057294990.SGD","LU2087621335.USD","LU2112291526.USD","BK4550","BK4585","LU0345769128.USD","BK4568","LU1032955483.USD","LU0203347892.USD","LU2133065610.SGD","LU2430703095.HKD","LU2430703251.USD","LU1244550494.USD","LU0345770993.USD","SG9999002224.SGD","LU0058720904.USD","LU1732800096.USD","BK4532","LU0345769631.USD","LU1585245621.USD","IE0034235303.USD","LU1061106388.HKD","LU1894683264.USD","BK4566","LU1778281490.HKD","IE000M9KFDE8.USD","IE00BKVL7J92.USD","LU1506573853.SGD"],"gpt_icon":0},{"id":"2517510824","title":"Pfizer Appoints Ex-J&J Leader to Accelerate Weight Loss Solutions","url":"https://stock-news.laohu8.com/highlight/detail?id=2517510824","media":"GuruFocus.com","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517510824?lang=en_us&edition=fundamental","pubTime":"2025-03-08 01:47","pubTimestamp":1741369645,"startTime":"0","endTime":"0","summary":"Pfizer  is stepping up its obesity drug development by naming James List as its new chief internal medicine officer, according to a Friday press release. The former Johnson & Johnson  executive brings extensive expertise from his post?GuruFocus has detected 6 Warning Signs with PFE.Based in New York, the pharmaceutical giant is refocusing its R&D efforts to fast?track development of cardiovascular, metabolic, hematologic, and obesity treatments. List previously led global therapeutic initiatives at J&J's Janssen unit, emphasizing his background in managing complex drug portfolios.The move comes as Pfizer intensifies competition in the obesity market, currently dominated by Eli Lilly  and Novo Nordisk . A recent TD Cowen note indicated that the duopoly is expected to persist until 2030. In 2023, Pfizer discontinued its twice?daily oral obesity regimen due to adverse side effects, shifting attention toward a once?The appointment is part of Pfizer's broader strategy to enhance its anti?ob","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pfizer-appoints-ex-j-j-174725403.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00B4R5TH58.HKD","BK4534","LU0912757837.SGD","LU0225771236.USD","IE0009355771.USD","PFE","LU0792757196.USD","LU0345770308.USD","LU1935042991.SGD","BK4007","LU0234572021.USD","LU1674673428.USD","BK4559","LU2602419157.SGD","LU0170899867.USD","LU1894683348.USD","LU0122379950.USD","IE00B7SZLL34.SGD","IE00BFTCPJ56.SGD","JNJ","LU1059921491.USD","LU2089984988.USD","LU2129689431.USD","IE00B2B36J28.USD","SG9999003800.SGD","LU1929549753.HKD","LU0882574055.USD","LU1244550577.SGD","BK4585","LU1280957306.USD","IE00BLSP4239.USD","LU0203347892.USD","LU2133065610.SGD","LU0320765646.SGD","LU1244550494.USD","LU1674673691.USD","LU1032466523.USD","LU1585245621.USD","LU0868494617.USD","LU0098860793.USD","IE0002141913.USD","LU1061106388.HKD","IE00BJT1NW94.SGD","SG9999013999.USD","LU1894683264.USD","AAQC","SG9999001440.SGD","LU2112291526.USD","LU1244550221.USD","LU1506573853.SGD"],"gpt_icon":1},{"id":"2517538457","title":"JNJ Halts Development of Depression Drug Over Efficacy Concerns","url":"https://stock-news.laohu8.com/highlight/detail?id=2517538457","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517538457?lang=en_us&edition=fundamental","pubTime":"2025-03-08 01:45","pubTimestamp":1741369500,"startTime":"0","endTime":"0","summary":"Johnson & Johnson JNJ decided to discontinue the Phase 3 VENTURA development program, which is evaluating aticaprant as an adjunctive treatment for major depressive disorder .Though data from the VENTURA program did confirm that the J&J drug was safe and well-tolerated in study participants, the decision to stop developing it for MDD indication is due to ‘insufficient efficacy in the target patient population.’ However, the pharma giant still intends to explore aticaprant’s potential ‘in other areas of high unmet need.’。J&J is currently undergoing full analyses of data from the VENTURA program and intends to share the same at a future medical meeting.This comes as a setback to J&J, which had high expectations for aticaprant in the MDD indication. The company has forecasted generating annual peak sales in the range of $1-$5 billion from the drug in the now-abandoned indication.J&J Reiterates Long-Term View for Innovative Medicine Biz","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/jnj-halts-development-depression-drug-174500525.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE0002270589.USD","IE00BDGV0183.EUR","LU1267930813.SGD","LU0795875086.SGD","LU0792757196.USD","LU1732799900.SGD","IE00BJT1NW94.SGD","LU0122379950.USD","LU0912757837.SGD","LU0234572021.USD","LU2129689514.USD","LU1066051225.USD","LU0289739699.SGD","ABVC","LU2468319806.SGD","LU1057294990.SGD","SG9999002224.SGD","IE00BGHQF631.EUR","LU1061106388.HKD","LU1261432733.SGD","LU0098860793.USD","BK4532","IE00B19Z3581.USD","LU0234570918.USD","LU1066051498.USD","LU2505996681.GBP","IE00BVYPNV92.GBP","LU2602419157.SGD","LU0345769631.USD","BK4581","IE00B19Z3B42.SGD","IE000M9KFDE8.USD","LU1059921491.USD","ITCI","IE00B1BXHZ80.USD","LU1674673691.USD","LU0058720904.USD","IE00BJJMRZ35.SGD","IE0002141913.USD","LU1732800096.USD","NMRA","SG9999001440.SGD","JNJ","LU0889566641.SGD","IE00BFTCPJ56.SGD","BK4533","IE00BSNM7G36.USD","LU2430703178.SGD","LU2112291526.USD","IE00B2B36J28.USD"],"gpt_icon":0}],"pageSize":16,"totalPage":13,"pageCount":2,"totalSize":200}]}}