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Lin, MD, PhD, Professor of Radiation Oncology at MD Anderson. \"These interim results showing that NKTR-255 can rapidly restore absolute lymphocyte counts post chemoradiation suggest that NKTR-255","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/rtboK12ORMgNOQ6pHWHlMg--~B/aD04Mzt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/ed402d287488a53ce89b92f9b5ed2bb0","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/rtboK12ORMgNOQ6pHWHlMg--~B/aD04Mzt3PTQwMDthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/prnewswire.com/ed402d287488a53ce89b92f9b5ed2bb0"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/nektar-collaborators-present-breaking-results-151500380.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/nektar-collaborators-present-breaking-results-151500380.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00B19Z4B17.USD","BK4080","SITC","BK4534","BK4198","IE00B66KJ199.SGD","IE0031619046.USD","NKTR","ALC","BK4007","IE00B7SZL793.SGD","LU2265009873.SGD","BK4157","AEIS","LU1804176565.USD","BK4231"],"gpt_icon":0},{"id":"2481167412","title":"AbCellera Presents Data on Applications of T-Cell Engager Platform at SITC 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2481167412","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481167412?lang=en_us&edition=fundamental","pubTime":"2024-11-07 23:05","pubTimestamp":1730991900,"startTime":"0","endTime":"0","summary":"VANCOUVER, British Columbia, November 07, 2024----AbCellera  today announced new data on its T-cell engager  platform, to be presented as a poster at the Society for Immunotherapy of Cancer  39th Annual Meeting at the George R. Brown Convention Center in Houston, Texas.AbCellera’s presentation, which is available for viewing here, describes:. Strategies to address key challenges in TCE development:. CD3-binding antibodies to widen the therapeutic window by generating TCEs with potent tumor-cell killing and optimal cytokine release. Molecules to enhance efficacy for solid tumor indications by increasing T-cell activation and proliferation through costimulation of CD28 and 4-1BB. Application of the platform to two of AbCellera’s TCE programs:. This press release contains forward-looking statements, including statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. The forward-looking statements are based on management’s current belie","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/Sm4Ot_7GUWiuwnma7JAp.w--~B/aD0zMzk7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/c2e84e927191472ec578af0702ab0e6e","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/Sm4Ot_7GUWiuwnma7JAp.w--~B/aD0zMzk7dz00ODA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/business-wire.com/c2e84e927191472ec578af0702ab0e6e"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/abcellera-presents-data-applications-t-150500517.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["ABCL","BK4231","SITC","BK4080","BK4121","BK4535"],"gpt_icon":0},{"id":"2481810551","title":"MiNK’s iNKT Cell Therapy Shows Potential for Optimal Multi-Combination for Resistant Solid Cancers at SITC 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2481810551","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481810551?lang=en_us&edition=fundamental","pubTime":"2024-11-07 23:00","pubTimestamp":1730991600,"startTime":"0","endTime":"0","summary":"AgenT-797 Combination with Checkpoint Inhibitors and Bispecific Engagers Expands Anti-Cancer Benefit PRAME-TCR iNKT Overcomes Challenges from Conventional TCR-T Cells in Solid Cancers NEW YORK, Nov.  ","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/07/2976856/0/en/MiNK-s-iNKT-Cell-Therapy-Shows-Potential-for-Optimal-Multi-Combination-for-Resistant-Solid-Cancers-at-SITC-2024.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["INKT","BK4139","BK4080","BK1103","SITC","IE00B12V2V27.USD","IE00BYTNYN87.SGD","SG9999011746.SGD","BK4231","IE00BYQNZ168.SGD","01308","BK1541"],"gpt_icon":0},{"id":"2481184289","title":"Phio Pharmaceuticals Announces Upcoming Presentation at the 39th Annual Meeting of the Society for Immunotherapy of Cancer (SITC)","url":"https://stock-news.laohu8.com/highlight/detail?id=2481184289","media":"Newsfile","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481184289?lang=en_us&edition=fundamental","pubTime":"2024-11-07 23:00","pubTimestamp":1730991600,"startTime":"0","endTime":"0","summary":"Presenting new clinical data from Phio's on-going Phase 1b trial. Marlborough, Massachusetts-- - Phio Pharmaceuticals Corp.  is a clinical-stage biotechnology company creating new pathways towards a cancer-free future by using its INTASYL siRNA gene silencing technology designed to make the body's immune cells more effective in killing cancer cells. Phio announced today that it is presenting clinical data from its on-going Phase 1b clinical trial at the 39th Annual Meeting of the Society for Immunotherapy of Cancer , which will be held in Houston, TX from November 8-10, 2024.Phio's presentation will highlight the clinical results from enrolled patients in Cohorts 1 and 2 in the Phase 1b dose escalation clinical trial. This clinical trial is designed to evaluate the safety and tolerability of intratumoral injection of PH-762 in patients with cutaneous squamous carcinoma, Merkel cell carcinoma and melanoma.Complete response  reported for 1 patient with cutaneous squamous cell carcinoma; ","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/DVTPo7Rq2WBAy4bw89tDjA--~B/aD00MDA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/newsfile_64/14a6f3219e9ec595846477ae166acc6a","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/DVTPo7Rq2WBAy4bw89tDjA--~B/aD00MDA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/newsfile_64/14a6f3219e9ec595846477ae166acc6a"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/phio-pharmaceuticals-announces-upcoming-presentation-150000990.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/phio-pharmaceuticals-announces-upcoming-presentation-150000990.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0107464264.USD","BK4080","BK4139","LU2517655028.SGD","BK4134","LU2517655374.HKD","SITC","IT","LU0154245756.USD","LU2517655291.USD","LU0154245673.USD","BK4585","PHIO","BK4231","LU1814569148.SGD","BK4588"],"gpt_icon":0},{"id":"2481181068","title":"IMUNON Presents Positive Data from Phase 2 OVATION 2 Clinical Trial of IMNN-001 in Advanced Ovarian Cancer at SITC 39th Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2481181068","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481181068?lang=en_us&edition=fundamental","pubTime":"2024-11-07 23:00","pubTimestamp":1730991600,"startTime":"0","endTime":"0","summary":"IMNN-001 immunotherapy plus standard-of-care chemotherapy resulted in 35% improvement in overall survival and 25% improvement in progression-free survival versus standard-of-care alone Treatment was g","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/07/2976849/0/en/IMUNON-Presents-Positive-Data-from-Phase-2-OVATION-2-Clinical-Trial-of-IMNN-001-in-Advanced-Ovarian-Cancer-at-SITC-39th-Annual-Meeting.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00BYQNZ168.SGD","SITC","BK4139","AEIS","SG9999011746.SGD","BK4211","OS","BK4097","IE00B19Z4B17.USD","IE00B12V2V27.USD","BK4195","BK4157","PFS","01308","IE00B7SZL793.SGD","IE00B66KJ199.SGD","IE00BYTNYN87.SGD","BK1103","BK4231","BK1541","IMNN","BK4080","IE0031619046.USD"],"gpt_icon":0},{"id":"2481181056","title":"Agenus to Present Compelling Data on Botensilimab and AGEN1721 at SITC 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2481181056","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481181056?lang=en_us&edition=fundamental","pubTime":"2024-11-07 23:00","pubTimestamp":1730991600,"startTime":"0","endTime":"0","summary":"Novel Candidates Show Promise in Turning Cold and Refractory Tumors into Responsive Targets. LEXINGTON, Mass., November 07, 2024----Agenus Inc.  , a leader in developing novel immunological agents to treat various cancers, today announced the presentation of new data on two of its promising investigational immunotherapy candidates, botensilimab and AGEN1721, at the Society for Immunotherapy of Cancer  2024 Annual Meeting in Houston, Texas. The data, showcasing potential breakthroughs in treating immune-resistant tumors, will be presented by Dhan Chand, Ph.D., Vice President of Research at Agenus.The first two presentations will spotlight botensilimab, an innovative, investigational, Fc-enhanced anti-CTLA-4 antibody that has shown remarkable efficacy in overcoming immune barriers across several treatment-resistant cancers, including glioblastoma, melanoma, colorectal, pancreatic, and breast cancers. Botensilimab’s unique mechanism of action enhances both innate and adaptive immunity to ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/agenus-present-compelling-data-botensilimab-150000687.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4231","BK4139","BK4080","SITC","AGEN"],"gpt_icon":0},{"id":"2481218342","title":"Xilio Therapeutics Announces Initial Clinical Trial Data from Phase 1C Dose Escalation for Vilastobart (XTX101), a Tumor-Activated Anti-CTLA-4, in Combination with Atezolizumab in Patients with Advanced Solid Tumors","url":"https://stock-news.laohu8.com/highlight/detail?id=2481218342","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481218342?lang=en_us&edition=fundamental","pubTime":"2024-11-07 22:15","pubTimestamp":1730988900,"startTime":"0","endTime":"0","summary":"Combination of vilastobart and atezolizumab demonstrated encouraging early evidence of anti-tumor activity, including unconfirmed partial responses observed in two patients with difficult-to-treat, im","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/07/2976781/0/en/Xilio-Therapeutics-Announces-Initial-Clinical-Trial-Data-from-Phase-1C-Dose-Escalation-for-Vilastobart-XTX101-a-Tumor-Activated-Anti-CTLA-4-in-Combination-with-Atezolizumab-in-Pati.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["IE00B7SZL793.SGD","LU2039709279.SGD","IE00B12V2V27.USD","BK4509","BK4107","BK4531","BK4585","LU0359202008.SGD","ALT","BK4080","BK4565","BK4588","LU1878469433.USD","AST","LU1023057109.AUD","01698","IE0031619046.USD","IE00B66KJ199.SGD","BK4548","BK4571","LENZ","BK4552","BK4231","BK4563","IE00B19Z4B17.USD","BK4108","L","LU0053666078.USD","BK4535","IE00BYQNZ168.SGD","BK4526","IE00BYTNYN87.SGD","TME","AEIS","LU0359201612.USD","BK4139","SG9999011746.SGD","SITC","BK4157"],"gpt_icon":0},{"id":"2481188424","title":"Press Release: Xilio Therapeutics Announces Pipeline and Business Updates and Third Quarter 2024 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2481188424","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481188424?lang=en_us&edition=fundamental","pubTime":"2024-11-07 22:05","pubTimestamp":1730988300,"startTime":"0","endTime":"0","summary":"Will present initial Phase 1C dose escalation data for vilastobart , a tumor-activated, Fc-enhanced anti-CTLA-4, in combination with atezolizumab, in a late-breaker poster presentation at the SITC Annual Meeting. Expect to report initial Phase 2 data in microsatellite stable colorectal cancer  for vilastobart in combination with atezolizumab in the fourth quarter of 2024. Expect to report Phase 1 data for XTX301, a tumor-activated IL-12, in the fourth quarter of 2024. WALTHAM, Mass., Nov. 07, 2024  -- Xilio Therapeutics, Inc. , a clinical-stage biotechnology company discovering and developing tumor-activated immuno-oncology therapies for people living with cancer, today announced pipeline progress and business updates and reported financial results for the third quarter ended September 30, 2024.","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU0359202008.SGD","BK4531","IE00BYQNZ168.SGD","SITC","BK4139","SG9999011746.SGD","BK4571","BK4552","BK4232","XLO","LENZ","BK4022","IE00B12V2V27.USD","BK4108","TME","LU0359201612.USD","BK4526","BK4535","BK4565","BK4563","BK4548","BK4509","R","01698","IE00BYTNYN87.SGD","BK4231","LU2039709279.SGD","BK4080","LU1023057109.AUD"],"gpt_icon":0},{"id":"2481887491","title":"Werewolf Therapeutics Presents Preclinical and Clinical Data at the Society for Immunotherapy of Cancer’s (SITC) 39th Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2481887491","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481887491?lang=en_us&edition=fundamental","pubTime":"2024-11-07 22:02","pubTimestamp":1730988120,"startTime":"0","endTime":"0","summary":"- Interim phase 1 clinical trial update reveals the clinical potential of the tumor-activated IL-12 prodrug WTX-330, with favorable tolerability profile and encouraging efficacy signals - - Additional","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.globenewswire.com/news-release/2024/11/07/2976763/0/en/Werewolf-Therapeutics-Presents-Preclinical-and-Clinical-Data-at-the-Society-for-Immunotherapy-of-Cancer-s-SITC-39th-Annual-Meeting.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4080","IE00BYQNZ168.SGD","BK1103","IE00B12V2V27.USD","HOWL","IE00BYTNYN87.SGD","BK1541","BK4539","BK4231","BK4139","SG9999011746.SGD","LENZ","01308","SITC"],"gpt_icon":0},{"id":"2481904186","title":"Indaptus Therapeutics Presents Encouraging Interim Safety Data from Phase 1 Clinical Trial of Decoy20 at the Society for Immunotherapy of Cancer (SITC) 2024 Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2481904186","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481904186?lang=en_us&edition=fundamental","pubTime":"2024-11-07 21:00","pubTimestamp":1730984400,"startTime":"0","endTime":"0","summary":"Data further confirms Company’s “Pulse-Prime” hypothesis. NEW YORK, Nov. 07, 2024  -- Indaptus Therapeutics, Inc.  , a clinical stage biotechnology company dedicated to pioneering innovative cancer and viral infection treatments, announces compelling safety, pharmacokinetics, and biomarker data on its lead compound, Decoy20, at the Society for Immunotherapy of Cancer  2024 annual meeting. The data derive from two cohorts  of Decoy20 single administration and one cohort  of Decoy20 weekly administration in the Company’s ongoing Phase 1 clinical trial. The SITC conference is being held November 6-10, 2024 in Houston, Tex.Indaptus Therapeutics has evolved from more than a century of immunotherapy advances. The Company’s novel approach is based on the hypothesis that efficient activation of both innate and adaptive immune cells and pathways and associated anti-tumor and anti-viral immune responses will require a multi-targeted package of immune system-activating signals that can be adminis","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/3XXQS3YWdGJ1JC2JJgEReg--~B/aD02MDt3PTIyNjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/7ccb73735e7b3453e7f55361e2fdf8ed","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/3XXQS3YWdGJ1JC2JJgEReg--~B/aD02MDt3PTIyNjthcHBpZD15dGFjaHlvbg--/https://media.zenfs.com/en/globenewswire.com/7ccb73735e7b3453e7f55361e2fdf8ed"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/indaptus-therapeutics-presents-encouraging-interim-130000687.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","SITC","INDP","BK4139","NLR","BK4231","BK4080"],"gpt_icon":0},{"id":"2481906520","title":"Press Release: Carisma Therapeutics Reports Third Quarter 2024 Financial Results and Recent Business Highlights","url":"https://stock-news.laohu8.com/highlight/detail?id=2481906520","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481906520?lang=en_us&edition=fundamental","pubTime":"2024-11-07 20:30","pubTimestamp":1730982600,"startTime":"0","endTime":"0","summary":"Initial results from the Phase 1 study of CT-0525, lead product candidate, expected in the first quarter of 2025. Nomination of a development candidate for liver fibrosis program expected in the first quarter of 2025. New preclinical efficacy data from the anti-GPC3 in vivo CAR-M therapy to be presented on November 8 at SITC 2024 Annual Meeting. \"Our recent progress across clinical and preclinical programs demonstrates our commitment to pioneering therapies that address significant unmet medical needs,\" said Steven Kelly, President and CEO of Carisma Therapeutics. \"We are advancing on multiple fronts. We expect to report initial data from the Phase 1 study of CT-0525 in the first quarter of 2025. We also recently nominated our first development candidate in hepatocellular carcinoma with Moderna and are excited to bring additional in vivo CAR-M therapies forward, including autoimmune targets. Our liver fibrosis program is progressing as well, with the nomination of a development candida","market":"sh","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BK4080","BK4139","CARM","SITC","BK4006","BK4230","BK4232","CAR","HCC","TIP","R","BK4585","BK4231","BK4022","BK4588"],"gpt_icon":0},{"id":"2481990804","title":"Press Release: Cullinan Therapeutics Provides Corporate Update and Reports Third Quarter 2024 Financial Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2481990804","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481990804?lang=en_us&edition=fundamental","pubTime":"2024-11-07 20:01","pubTimestamp":1730980860,"startTime":"0","endTime":"0","summary":"Global Phase 1 study of CLN-978 in systemic lupus erythematosus  cleared to initiate in U.S. and Australia; initial clinical data expected in Q4 2025. CLN-619 on-track for initial expansion cohort data in endometrial and cervical cancers in Q2 2025. \"We are making meaningful progress in executing our strategic plans for CLN-978 in autoimmune diseases while simultaneously advancing our oncology pipeline,\" said Nadim Ahmed, Chief Executive Officer of Cullinan Therapeutics. \"We have secured clearance from the U.S. Food and Drug Administration  for our IND application and Human Research Ethics Committee  approval in Australia to initiate our global Phase 1 study for CLN-978 in moderate to severe SLE. These important regulatory clearances position us to share initial clinical data for CLN-978 in the fourth quarter of 2025. We also continue to make significant progress in advancing our oncology portfolio, with data from two of our key programs expected in 2025. For CLN-619, we remain on trac","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["RA","ACR","SITC","BK4139","BK4110","BK4231","BK4077","CGEM","SLE","BK4080"],"gpt_icon":0},{"id":"2481952610","title":"Arcus Biosciences Reports Third-Quarter 2024 Financial Results and Provides a Pipeline Update","url":"https://stock-news.laohu8.com/highlight/detail?id=2481952610","media":"Business Wire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481952610?lang=en_us&edition=fundamental","pubTime":"2024-11-07 05:22","pubTimestamp":1730928120,"startTime":"0","endTime":"0","summary":"Data from the Phase 1/1b ARC-20 study of casdatifan were presented at an oral plenary session at the 2024 EORTC-NCI-AACR Symposium; a low rate of primary progression (19%) and promising objective response rate  for the 100mg daily  cohort of heavily pretreated patients with clear-cell renal cell carcinoma  support a potential best-in-class profile. Arcus announced a clinical trial collaboration agreement with AstraZeneca to evaluate casdatifan in combination with volrustomig, an investigational PD-1/CTLA-4 bispecific antibody, in patients with immuno-oncology -naive ccRCC. Data from the randomized ARC-10 study will be presented at the Annual Meeting of the Society of Immunotherapy of Cancer ; domvanalimab plus zimberelimab reduced the risk of death in first-line metastatic non-small cell lung cancer  by 36% compared to zimberelimab. In October 2024, Arcus announced a clinical collaboration with AstraZeneca to evaluate casdatifan in combination with volrustomig, AstraZeneca’s investigat","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/arcus-biosciences-reports-third-quarter-212200285.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0053666078.USD","BK4139","QD","BK4231","BK4166","L","RCUS","BK4563","SITC","BK4503","BK4080","BK4585","BK4195","BK4107","BK4211","BK4179","PFS","BK4588","IO"],"gpt_icon":0},{"id":"2481659827","title":"NextCure Reports Preclinical Data for LNCB74 and Additional Clinical Biomarker Data for NC410 Combo at Society for Immunotherapy of Cancer Annual Meeting","url":"https://stock-news.laohu8.com/highlight/detail?id=2481659827","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481659827?lang=en_us&edition=fundamental","pubTime":"2024-11-06 05:05","pubTimestamp":1730840700,"startTime":"0","endTime":"0","summary":"Preclinical data for LNCB74 highlights its potential as therapeutic for treating multiple solid tumor indications; Investigational New Drug  application filing expected by year-end. Additional biomarker data support proposed mechanism of action of NC410. “The preclinical data reported for LNCB74, our B7-H4 antibody-drug conjugate program, continue to reinforce its promise as a potential best-in-class therapeutic with advantages over other B7-H4 ADCs,” said Michael Richman, NextCure’s president and CEO. “We remain on track to submit an IND application to the FDA by year-end and intend to rapidly advance the program into clinical development.”Preclinical Data on LNCB74 B7-H4 Antibody Drug Conjugate . LNCB74 demonstrates strong anti-tumor activity in multiple CDX and PDX tumor models. A single dose of 3 mg/kg resulted in durable tumor regression in multiple tumor models, sugges","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/Bv.beZU4rhPKHBxYht4rYQ--~B/aD00NjY7dz0yNzAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/globenewswire.com/462268a5ee7f2d042d612b6f9f35a927","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/Bv.beZU4rhPKHBxYht4rYQ--~B/aD00NjY7dz0yNzAwO2FwcGlkPXl0YWNoeW9u/https://media.zenfs.com/en/globenewswire.com/462268a5ee7f2d042d612b6f9f35a927"],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/nextcure-reports-preclinical-data-lncb74-210500749.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU0266512127.USD","BK4080","BK4213","LU0456854461.SGD","SITC","BK4231","BK4113","ADC","BK4139","CRC","NXTC","MSS"],"gpt_icon":0},{"id":"2481565952","title":"Poseida Therapeutics to Present Clinical and Preclinical Data on Investigational Allogeneic CAR-T Cell Therapies at SITC 2024 and ASH 2024","url":"https://stock-news.laohu8.com/highlight/detail?id=2481565952","media":"PR Newswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2481565952?lang=en_us&edition=fundamental","pubTime":"2024-11-06 05:05","pubTimestamp":1730840700,"startTime":"0","endTime":"0","summary":"New preclinical data on allogeneic CAR+TCR-T cells rich in stem cell memory T cells  and enhanced potency to better target solid tumors will be presented at SITC. Additional profiling of patient responses in P-BCMA-ALLO1 Phase 1 Arm C and preclinical P-CD19CD20-ALLO1 to be presented at ASH. SAN DIEGO, Nov. 5, 2024 /PRNewswire/ --Poseida Therapeutics, Inc. , a clinical-stage allogeneic cell therapy and genetic medicines company advancing differentiated non-viral treatments for patients with cancer, autoimmune and rare diseases, today announced new preclinical data on allogeneic CAR+TCR-T cells rich in stem cell memory T cells , along with platform enhancements aimed at enhancing potency and improving targeting of solid tumors, will be presented at the Society for Immunotherapy of Cancer  39thAnnual Meeting in Houston, November 6-10.","market":"us","thumbnail":"https://s.yimg.com/uu/api/res/1.2/0ZbecZcTygdfn10jwwgw3w--~B/aD0yOTA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/4f05f1549db26db37f15a45f2f462010","type":0,"news_type":0,"thumbnails":["https://s.yimg.com/uu/api/res/1.2/0ZbecZcTygdfn10jwwgw3w--~B/aD0yOTA7dz00MDA7YXBwaWQ9eXRhY2h5b24-/https://media.zenfs.com/en/prnewswire.com/4f05f1549db26db37f15a45f2f462010"],"rights":{"source":"yahoofinance","url":"https://finance.yahoo.com/news/poseida-therapeutics-present-clinical-preclinical-210500162.html","rn_cache_url":null,"customStyle":"img, svg { display: none !important; }","selectors":"article","filters":"","directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/poseida-therapeutics-present-clinical-preclinical-210500162.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LENZ","BK4080","BK4230","PSTX","BK4231","ASH","LU2463526074.USD","BK4109","BK4022","SITC","BK4139","CAR"],"gpt_icon":0}],"pageSize":16,"totalPage":13,"pageCount":6,"totalSize":198}]}}