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Therapeutics Shares Hit 52-Week High on Hypertension Study Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2518837227","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518837227?lang=en_us&edition=fundamental","pubTime":"2025-03-10 21:57","pubTimestamp":1741615020,"startTime":"0","endTime":"0","summary":"Mineralys Therapeutics shares surged to a new 52-week high Monday after the clinical-stage biopharmaceutical company reported positive study results for its lorundrostat drug candidate for the treatment of uncontrolled or resistant hypertension.Shares of the Radnor, Pa., company were recently changing hands at $15.07, up 43%, after touching a 52-week high of $15.64 early in the session.Mineralys said a pair of pivotal studies of lorundrostat achieved statistical significance and were clinically meaningful in their pre-specified primary efficacy endpoints, and that the results demonstrate the opportunity for 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Therapeutics Says Lorundrostat Met Trial Endpoints for Treating Hypertension; Shares Up Pre-Bell","url":"https://stock-news.laohu8.com/highlight/detail?id=2518223344","media":"MT Newswires Live","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518223344?lang=en_us&edition=fundamental","pubTime":"2025-03-10 20:12","pubTimestamp":1741608769,"startTime":"0","endTime":"0","summary":"Mineralys Therapeutics  shares were up premarket Monday after the company said lorundrostat met primary endpoints in both the phase 3 Launch-HTN and phase 2 Advance-HTN trials in patients with uncontrolled hypertension or resistant hypertension.The company said the phase 3 study showed a statistically significant drop in systolic blood pressure compared with placebo by week six until week 12.In the phase 2 trial, lorundrostat also led to a statistically significant placebo-adjusted drop of 7.9 mmHg in systolic pressure at week 12, Mineralys said.Mineralys said the treatment was generally well tolerated in both studies, with low rates of serious side effects and elevated potassium levels. The company said it plans to present more data at a medical conference later this month and continue collecting longer-term results in an extension study.","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BK4139","MLYS","LENZ"],"gpt_icon":0},{"id":"2518824714","title":"Mineralys Therapeutics Shares Resume Trading, Jump 40% Premarket After Co's Blood Pressure Drug Meets Goal in Trials","url":"https://stock-news.laohu8.com/highlight/detail?id=2518824714","media":"THOMSON REUTERS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518824714?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:31","pubTimestamp":1741606310,"startTime":"0","endTime":"0","summary":null,"market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250310:nL4N3PT0UH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"reuters_en_live","symbols":["MLYS","BK4139"],"gpt_icon":0},{"id":"2518624785","title":"CORRECTED-UPDATE 2-Mineralys' blood pressure drug meets goal in trials, shares soar","url":"https://stock-news.laohu8.com/highlight/detail?id=2518624785","media":"Reuters","labels":["dataReport","event"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518624785?lang=en_us&edition=fundamental","pubTime":"2025-03-10 19:22","pubTimestamp":1741605768,"startTime":"0","endTime":"0","summary":"CORRECTED-UPDATE 2-Mineralys' blood pressure drug meets goal in trials, shares soarCorrects paragraph 3 to say the drug showed reduction of 7.9 mmHg, not 11.7 mmHg, in mid-stage studyMarch 10  - Mineralys Therapeutics MLYS.O said on Monday its experimental  drug met the main goal of lowering blood pressure in patients with uncontrolled or resistant hypertension in late- and mid- stage trials, sending its shares up about 43% before the bell.In the late-stage study, the treatment called lorundrostat showed a placebo-adjusted reduction in systolic blood pressure by 9.1 mmHg  at week six. The benefit was sustained through week 12, with a further reduction to 11.7 mmHg.The drug also reduced systolic blood pressure by 7.9 mmHg in a mid-stage trial when compared to a placebo, the company said.Lorundrostat inhibits the production of aldosterone, a hormone that can contribute to high blood pressure.  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Solutions","url":"https://stock-news.laohu8.com/highlight/detail?id=2517460682","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517460682?lang=en_us&edition=fundamental","pubTime":"2025-03-08 07:28","pubTimestamp":1741390080,"startTime":"0","endTime":"0","summary":"Cognizant Technology Solutions said it has been constructively engaging with Mantle Ridge, an activist firm that has built up a more than $1 billion stake in the company. Mantle Ridge believes shares of the tech-services firm are undervalued and has been privately engaging with Cognizant about its progress on boosting the share price, The Wall Street Journal reported, citing people familiar with the matter. Shares rise 5.2%, to $87.54, in after-hours trading.Mineralys Therapeutics said it plans to release data from two recent trials involving lorundrostat, a drug the biopharmaceutical company is developing as a treatment for high blood pressure. Shares gain 12%, to $11.82, in postmarket trading.PDF Solutions closed a $130 million acquisition and entered into a new credit agreement. The company, which provides data solutions for the semiconductor and electronics industries, said its acquisition of SecureWise will significantly expand its manufacturing connectivity network. It also enter","market":"other","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LU2087621335.USD","LU1048596156.SGD","LENZ","LU0231203729.USD","BK4139","BK4585","LU0072462343.USD","LU1267930656.SGD","LU2506951875.HKD","LU0006061336.USD","LU1839511570.USD","CTSH","LU2506952170.USD","PDFS","BK4147","LU0950375773.USD","LU0823417737.USD","MLYS","BK4588","BK4134","LU1048588211.SGD","LU2506952097.USD","LU0823417653.USD","LU0821914370.USD","LU2506951958.HKD","LU0536402901.SGD","LU0708995666.HKD"],"gpt_icon":1},{"id":"2517462720","title":"Mineralys Therapeutics Rises Ahead of Hypertension-Drug Trial Data","url":"https://stock-news.laohu8.com/highlight/detail?id=2517462720","media":"Dow Jones","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517462720?lang=en_us&edition=fundamental","pubTime":"2025-03-08 06:52","pubTimestamp":1741387920,"startTime":"0","endTime":"0","summary":"Shares of Mineralys Therapeutics gained after the company said it plans to release data from two recent trials involving lorundrostat, a drug the company is developing as a treatment for high blood pressure.The stock was up 13%, to $11.88, in after-hours trading Friday. Shares ended the regular session roughly flat and have lost a quarter of their value in the past year.The Radnor, Pa., biopharmaceutical company said after the bell that it would host a conference call and webinar to announce topline results from its Launch-HTN and Advance-HTN pivotal trials on Monday morning.The Launch-HTN trial evaluated lorundrostat as an add-on therapy to an existing, prescribed background treatment of two-to-five anti-hypertensive medications, while the Advance-HTN trial evaluated the drug as an add-on therapy to a standardized background treatment of two or three anti-hypertensive medications, the company said.","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["LENZ","MLYS","BK4139"],"gpt_icon":0}],"pageSize":16,"totalPage":5,"pageCount":2,"totalSize":72}]}}