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EpCAM  is a highly expressed tumor antigen that has been previously undruggable with systemically administered agents due to expression on normal tissues. CX-2051 is designed to open a therapeutic window for this high potential target and deliver meaningful anti-cancer activity in solid tumors, including CRC. CRC remains an area of high unmet medical need, especially in the late-line setting, where outcomes from currently approved standard of care remain extremely poor, with objective response rates in the low-single digit percentages and approximately two to f","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytomx-therapeutics-announces-2024-financial-211000884.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX","BK4139"],"gpt_icon":0},{"id":"2517291921","title":"CytomX Therapeutics to Present at the Barclays 27th Annual Global Healthcare Conference","url":"https://stock-news.laohu8.com/highlight/detail?id=2517291921","media":"GlobeNewswire","labels":["conferences"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517291921?lang=en_us&edition=fundamental","pubTime":"2025-03-05 21:00","pubTimestamp":1741179600,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif., March 05, 2025  -- CytomX Therapeutics, Inc. , a leader in the field of masked, conditionally activated biologics, today announced that Sean McCarthy, D.Phil., chief executive officer and chairman, will present at the Barclays 27th Annual Global Healthcare Conference on Wednesday, March 12, 2025, at 3:00 p.m. ET.A live webcast of the presentation will be available on the Events and Presentations page of CytomX’s website at www.cytomx.com. In addition, management will be available for one-on-one meetings with investors who are registered to attend the conferences.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytomx-therapeutics-present-barclays-27th-130000088.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"conferences","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["HCSG","BK4137","CTMX","BK4139"],"gpt_icon":0},{"id":"2517881989","title":"CytomX Therapeutics Inc  expected to post a loss of 20 cents a share - Earnings Preview","url":"https://stock-news.laohu8.com/highlight/detail?id=2517881989","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517881989?lang=en_us&edition=fundamental","pubTime":"2025-03-05 05:08","pubTimestamp":1741122487,"startTime":"0","endTime":"0","summary":"CytomX Therapeutics Inc  expected to post a loss of20cents a share - Earnings Preview CytomX Therapeutics Inc CTMX.OQ CTMX.O is expected to show a fall in quarterly revenue when it reports  results on","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250304:nL5N3PN2MH:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["CTMX"],"gpt_icon":0},{"id":"2517609676","title":"CytomX Gears Up to Report Q4 Earnings: What Should Investors Expect?","url":"https://stock-news.laohu8.com/highlight/detail?id=2517609676","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2517609676?lang=en_us&edition=fundamental","pubTime":"2025-03-04 22:42","pubTimestamp":1741099320,"startTime":"0","endTime":"0","summary":"CytomX TherapeuticsCTMX, a clinical-stage oncology company, is slated to reportits fourth-quarter 2024 earnings results on March 6, after market close. The company leverages its proprietary PROBODYtherapeutic platform to discover and develop safer, more effective therapies for the treatment of cancer.See the ZacksEarnings Calendar to stay ahead of market-making news.The Zacks Consensus Estimate for CTMX’s loss per share in the to-be-reported quarter is currently pegged at 20 cents. CytomX also recognizes collaboration revenues from its ongoing partnership agreements with several biotech companies like Amgen AMGN, Astellas,Bristol Myers Squibb, Moderna and Regeneron. The Zacks Consensus Estimate for the company’s fourth-quarter revenues is pinned at $20.13 million.Let's see how things have shaped up for the upcoming quarterly release.CytomX will also reduce its workforce by about 40% to prioritize clinical programs and enhance financial flexibility. Management expects the resulting cost","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytomx-gears-report-q4-earnings-144200064.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["ISBC","CTMX"],"gpt_icon":0},{"id":"2514875804","title":"CytomX Therapeutics to Report Fourth Quarter and Full Year 2024 Financial Results on March 6, 2025","url":"https://stock-news.laohu8.com/highlight/detail?id=2514875804","media":"GlobeNewswire","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2514875804?lang=en_us&edition=fundamental","pubTime":"2025-02-27 21:00","pubTimestamp":1740661200,"startTime":"0","endTime":"0","summary":"SOUTH SAN FRANCISCO, Calif., Feb. 27, 2025  -- CytomX Therapeutics, Inc. , a leader in the field of masked, conditionally activated biologic therapeutics, today announced that it will report full year 2024 financial results on Thursday, March 6, 2025, after the close of U.S. markets. Following the announcement, the Company will host a conference call and webcast at5:00 p.m. ET/2:00 p.m. PT.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytomx-therapeutics-report-fourth-quarter-130000187.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX","BK4139"],"gpt_icon":0},{"id":"2508175666","title":"CytomX Therapeutics Announces Executive Departure and Severance","url":"https://stock-news.laohu8.com/highlight/detail?id=2508175666","media":"TIPRANKS","labels":["executive"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2508175666?lang=en_us&edition=fundamental","pubTime":"2025-02-04 05:36","pubTimestamp":1738618605,"startTime":"0","endTime":"0","summary":"An announcement from CytomX Therapeutics ( ($CTMX) ) is now available. On January 30, 2025, CytomX Therapeutics announced the termination of employ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/cytomx-therapeutics-announces-executive-departure-and-severance?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/cytomx-therapeutics-announces-executive-departure-and-severance?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"executive","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","CTMX"],"gpt_icon":0},{"id":"2507631655","title":"Shareholders in CytomX Therapeutics (NASDAQ:CTMX) are in the red if they invested five years ago","url":"https://stock-news.laohu8.com/highlight/detail?id=2507631655","media":"Simply Wall St.","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507631655?lang=en_us&edition=fundamental","pubTime":"2025-01-29 22:21","pubTimestamp":1738160475,"startTime":"0","endTime":"0","summary":"Long term investing is the way to go, but that doesn't mean you should hold every stock forever. It hits us in the gut when we see fellow investors suffer a loss. Anyone who held CytomX Therapeutics, Inc.  for five years would be nursing their metaphorical wounds since the share price dropped 89% in that time. And some of the more recent buyers are probably worried, too, with the stock falling 46% in the last year. Unfortunately the share price momentum is still quite negative, with prices down 21% in thirty days. While a drop like that is definitely a body blow, money isn't as important as health and happiness.So let's have a look and see if the longer term performance of the company has been in line with the underlying business' progress.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/shareholders-cytomx-therapeutics-nasdaq-ctmx-142115313.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["QLD","BK4588","NVIW.SI","IE00B3QW5Z07.USD","USJW.SI","LU2210150020.SGD","LU2095319765.USD","TQQQ","NDAQ","PSQ","BK4139","IE00BGHQF748.EUR","MNQmain","CTMX","LU2210149790.SGD",".IXIC","NQmain","BK4585","USAW.SI","BK4112","SQQQ","QID","IE00B64PRP62.GBP","TSYW.SI","IE00BKPKM429.USD"],"gpt_icon":1},{"id":"2507543472","title":"PFE Stock Rises on Reports of Averting Proxy Fight With Activist Investor","url":"https://stock-news.laohu8.com/highlight/detail?id=2507543472","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2507543472?lang=en_us&edition=fundamental","pubTime":"2025-01-28 23:22","pubTimestamp":1738077720,"startTime":"0","endTime":"0","summary":"Shares of Pfizer PFE rose nearly 3% on Monday following a report issued by Bloomberg, which stated that activist investor Starboard did not nominate any director to Pfizer’s board ahead of Jan. 25.With the expiry of the deadline, Starboard has foregone an opportunity to bring changes in PFE’s board. This signals a less confrontational approach, at least for this year. Shareholders are set to convene at Pfizer’s annual meeting in April to vote on director seats for the year.The article, however, pointed out that Starboard could still try to make the changes in Pfizer’s board next year if the two parties are unable to reach an agreement.Bloomberg claims to have contacted both Pfizer and Starboard, who have either declined to comment on the above news or are yet to respond.The above article provides some respite to Pfizer’s management, which was accused last year by Starboard of making poor capital allocation, research and development (R&D) failures and problems with forecasting and budge","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/pfe-stock-rises-reports-averting-152200714.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE000M9KFDE8.USD","LU1894683264.USD","BK4139","BK4568","LU1057294990.SGD","LU1894683348.USD","IE00B19Z3581.USD","IE0002270589.USD","LU0122379950.USD","SGXZ57979304.SGD","CTMX","PFE","CSTL","LU0321505868.SGD","ERAS","LU0289739699.SGD","LU1023059063.AUD","IE00BLSP4452.SGD","SG9999001176.SGD","IE00BLSP4239.USD","LU0306807586.USD","SG9999001176.USD","SG9999013999.USD","SG9999011175.SGD","SG9999002224.SGD","IE00BBT3K403.USD","BK4539","BK4196","BK4550","LU0225771236.USD","LU0225284248.USD","BK4599","LU0058720904.USD","LU0868494617.USD","BK4592","BK4533","IE00B19Z3B42.SGD","LU0170899867.USD","LU1066053197.SGD","LU0456855351.SGD","BK4585","SG9999002232.USD","LU1066051498.USD","LU1883839398.USD","LU0985481810.HKD","SG9999003800.SGD","LU0234572021.USD","BK4007","BK4534","BK4588"],"gpt_icon":0},{"id":"2505044214","title":"CYTK Stock Rises as Enrollment Begins in Phase II Heart Failure Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2505044214","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505044214?lang=en_us&edition=fundamental","pubTime":"2025-01-24 00:19","pubTimestamp":1737649140,"startTime":"0","endTime":"0","summary":"Shares of Cytokinetics CYTK gained 2.2% on Wednesday after the company began enrolling patients in its mid-stage study of CK-4021586 , a cardiac myosin inhibitor, for treating heart failure patients. The intended patient population includes those with symptomatic heart failure with preserved ejection fraction  with left ventricular ejection fraction  ≥60%.Cytokinetics plans to enroll approximately 60 HFpEF patients in the phase II AMBER-HFpEF study who will receive CK-586 or placebo in three dose escalation cohorts. In the past three months, CYTK shares have lost 10.6% compared with the industry’s 8.7% decline.Cytokinetics is developing its lead investigational candidate, aficamten, a novel, oral and small-molecule cardiac myosin inhibitor, to reduce the hypercontractility associated withhypertrophic cardiomyopathy . A regulatory filing for aficamten to treat obstructive HCM is currently under review by the FDA. A final decision from the regulatory body is expected on Sept. 26, 2025. T","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytk-stock-rises-enrollment-begins-161900028.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4007","BK4505","BK4531","BK4139","IE00B7SZLL34.SGD","IE0002270589.USD","HCM","IE00B19Z3581.USD","BK4585","BK4196","BK4566","CSTL","CYTK","IE00B19Z3B42.SGD","BK4588","CTMX","BMRN"],"gpt_icon":0},{"id":"2505489620","title":"Keros Therapeutics Stock Plunges 81% in 3 Months: Here's Why","url":"https://stock-news.laohu8.com/highlight/detail?id=2505489620","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505489620?lang=en_us&edition=fundamental","pubTime":"2025-01-23 22:13","pubTimestamp":1737641580,"startTime":"0","endTime":"0","summary":"Shares of Keros Therapeutics KROS, a clinical-stage biotech, have plunged 80.9% in the past three months. The massive decline was primarily due to the company’s voluntary decision to halt dosing in the ongoing mid-stage study of its pipeline candidate, cibotercept , to treat patients with pulmonary arterial hypertension , a kind of lung disease.Keros Therapeutics’ decision was based on unexpected adverse pericardial effusion events that were observed during the study's safety review by an independent data monitoring committee . Cibotercept is an investigational modified ActRIIB fusion protein.The phase II TROPOSstudy is evaluating three doses of cibotercept  in combination with background therapy to treat PAH patients. After consulting with the DMC, Keros Therapeutics initially chose to suspend dosing in the 3 mg/kg and 4.5 mg/kg treatment arms of the TROPOS study while continuing dosing in the 1.5 mg/kg arm. However, earlier this month, the company announced the suspension of dosing i","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/keros-therapeutics-stock-plunges-81-141300812.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00B19Z3B42.SGD","BK4566","IE00B7SZLL34.SGD","CSTL","KROS","BK4139","BK4196","CTMX","BMRN","IE00B19Z3581.USD","LENZ","IE0002270589.USD"],"gpt_icon":0},{"id":"2505230363","title":"AstraZeneca Secures FDA Nod for New ADC Drug Datroway in Breast Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2505230363","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505230363?lang=en_us&edition=fundamental","pubTime":"2025-01-21 03:05","pubTimestamp":1737399900,"startTime":"0","endTime":"0","summary":"AstraZeneca AZN announced that the FDA has approved its antibody-drug conjugate ,datopotamab deruxtecan , in patients with a certain type of breast cancer. The drug, developed in partnership with Japan-based Daiichi Sankyo, will be marketed under the brand name Datroway.Post the FDA’s approval, the ADC drug is approved to treat unresectable or metastatic HR-positive, HER2-negative breast cancer in adult patients who have received prior endocrine-based therapy and chemotherapy.This approval came just a few weeks after Daiichi secured approval for the drug for a similar indication in Japan. The approvals in the United States and Japan are based on data from the phase III TROPION-Breast01 study, which showed that treatment with Datroway significantly reduced the risk of disease progression or death by 37% compared to the investigator’s choice of chemotherapy in the above indication.Per AstraZeneca, Datroway is part of a select group of therapies that could achieve peak annual sales of at ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/astrazeneca-secures-fda-nod-adc-190500987.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["LU2417539215.USD","LU1829250122.USD","BK4585","LU2456880835.USD","CTMX","LU2462157665.USD","BK4568","BK4007","BK4139","ADC","ERAS","BK4539","BK4588","BK4080","BK4196","LU0889565916.HKD","AZN","LU0109394709.USD","LU2236285917.USD","BK4231","CSTL","LU0320765992.SGD"],"gpt_icon":0},{"id":"2505287123","title":"Amgen's Lumakras Gets FDA Nod for Expanded Use in Colorectal Cancer","url":"https://stock-news.laohu8.com/highlight/detail?id=2505287123","media":"Zacks","labels":["productRelease"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2505287123?lang=en_us&edition=fundamental","pubTime":"2025-01-20 22:18","pubTimestamp":1737382680,"startTime":"0","endTime":"0","summary":"Amgen AMGN announced that the FDA has approved its KRAS inhibitor, Lumakras , in combination with its anti-EGFR antibody, Vectibix , for treating KRAS G12C-mutated metastatic colorectal cancer .The regulatory body approved Lumakras plus Vectibix for treating KRAS G12C-mutated mCRC in adult patients who have previously received fluoropyrimidine-, oxaliplatin- and irinotecan-based chemotherapy.Lumakras is presently approved for treating advanced or metastatic non-small cell lung cancer . The drug was approved in the United States in May 2021 and in the EU  in January 2022.In the past year, shares of Amgen have dropped 12.2% compared with the industry’s decline of 14.1%.Lumakras’ approval for the mCRC indication was based on data from the phase III CodeBreaK 300 study, which evaluated Lumakras plus Vectibix versus the investigator's choice of therapy in KRAS G12C–mutated mCRC.Data from the CodeBreaK 300 study also showed that treatment with Lumakras plus Vectibix demonstrated favorable ov","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/amgens-lumakras-gets-fda-nod-141800343.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"2","news_top_title":null,"news_tag":"productRelease","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CSTL","CTMX","AMGN","IE00B4R5TH58.HKD","IE0009355771.USD","LU0122379950.USD","BK4211","LU0868494617.USD","BK4139","LU1057294990.SGD","LU2112291526.USD","VYGR","IE00BJT1NW94.SGD","BK4581","SOC","LU2242652126.USD","IE00BFTCPJ56.SGD","LU1061106388.HKD","LU0289739699.SGD","LU2242646821.SGD","IE00B2B36J28.USD","BK4588","BK4566","BK4533","IE0002141913.USD","LU1023059063.AUD","IE00BJJMRZ35.SGD","LU0109394709.USD","BK4599","LU0320765992.SGD","LU0058720904.USD","BK4213","BK4196","BK4195","BK4534","LU1571399168.USD","BK4585","LU1983299246.USD","PFS","SG9999001440.SGD","LU0889565916.HKD"],"gpt_icon":0},{"id":"2504929191","title":"Is it a Good Idea to Invest in Stoke Therapeutics Stock Now?","url":"https://stock-news.laohu8.com/highlight/detail?id=2504929191","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2504929191?lang=en_us&edition=fundamental","pubTime":"2025-01-17 23:28","pubTimestamp":1737127680,"startTime":"0","endTime":"0","summary":"Massachusett-based Stoke Therapeutics STOK is making rapid progress with the development of zorevunersen , its investigational candidate for treating Dravet syndrome, a severe and progressive genetic epilepsy.Zorevunersen is a novel proprietary antisense oligonucleotide with the potential to become the first disease-modifying therapy to address the genetic cause of Dravet syndrome.The FDA granted a Breakthrough Therapy designation to zorevunersen for treating Dravet syndrome in December 2024.In the past year, shares of Stoke Therapeutics have rallied 94.7% against the industry’s decline of 13.6%.In the past 60 days, estimates for Voyager Therapeutics’ loss per share have narrowed from $1.72 to $1.48 for 2025. In the past year, shares of VYGR have plunged 30.6%.In the past 60 days, estimates for CytomX Therapeutics’ loss per share have narrowed from 46 cents to 35 cents for 2025. In the past year, shares of CTMX have decreased 49.5%.CTMX’s earnings beat estimates in two of the trailing ","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/good-idea-invest-stoke-therapeutics-152800824.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","CSTL","STOK","CTMX","LENZ","BK4196","VYGR"],"gpt_icon":0},{"id":"2504195429","title":"ATRA Stock Down After FDA Issues CRL for Rare Blood Cancer Candidate","url":"https://stock-news.laohu8.com/highlight/detail?id=2504195429","media":"Zacks","labels":["policyRegulatory"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2504195429?lang=en_us&edition=fundamental","pubTime":"2025-01-17 22:24","pubTimestamp":1737123840,"startTime":"0","endTime":"0","summary":"Tab-cel, the company’s novel T-cell immunotherapy, is already marketed in the EU under the brand name, Ebvallo, by Atara’s partner Pierre Fabre under an exclusive commercialization and license agreement.EBV+ PTLD is a rare hematologic malignancy  with a high mortality rate and occurs after patients undergo transplantation when their T-cell immune responses are compromised by immunosuppression.In the past three months, Atara shares have lost 16.8% compared with the industry’s 12.2% decline.More on the FDA’s CRL Issuance Against ATRA’s Ebvallo. Atara is eligible to receive a $60 million milestone payment from Pierre Fabre upon FDA approval of the Ebvallo BLA, providing a critical cash infusion for the company. Additionally, it will be eligible for substantial double-digit tiered royalties based on net sales and further milestones tied to Ebvallo's commercial performance. However, the FDA's CRL has also delayed the milestone payment, impacting funds the company planned to allocate for sup","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/atra-stock-down-fda-issues-142400167.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-2","news_top_title":null,"news_tag":"policyRegulatory","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX","IE00B19Z3B42.SGD","LU0390134368.USD","BK4585","BK4196","ATRA","BK4121","BK4588","CRL","IE00B19Z3581.USD","BMRN","BK4566","CSTL","BK4139","IE00B7SZLL34.SGD","BK4530","IE0002270589.USD"],"gpt_icon":0},{"id":"2504949490","title":"MIRM Shares Rise 12% in a Week on Robust Preliminary 2024 Results","url":"https://stock-news.laohu8.com/highlight/detail?id=2504949490","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2504949490?lang=en_us&edition=fundamental","pubTime":"2025-01-17 01:09","pubTimestamp":1737047340,"startTime":"0","endTime":"0","summary":"Shares of Mirum Pharmaceuticals MIRM were up 12.1% this week, driven by investor enthusiasm after the company announced encouraging preliminary sales numbers for the fourth quarter and full year 2024, along with an encouraging outlook and growth strategy for 2025.Mirum’s commercial portfolio comprises of lead product, Livmarli , which is approved for treating cholestatic pruritus in patients with Alagille syndrome worldwide. The drug is also approved for treating certain patients with progressive familial intrahepatic cholestasis in the United States and Europe.MIRM acquired Travere Therapeutics’ bile acid products in August 2023, which added the latter’s Cholbam capsules and Chenodal tablets to its portfolio of commercialized drugs.In the past year, shares of Mirum have rallied 73.3% against the industry’s decline of 16%.Meanwhile, a new drug application seeking approval for Chenodiol for cerebrotendinous xanthomatosis  patients is currently under review in the United States. 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