CytomX Therapeutics

0.6697

+0.066010.93%

Post-market: 0.6600-0.0097-1.45%19:28 EDT

Volume:1.22M

Turnover:789.16K

Market Cap:53.64M

PE:1.77

High:0.6700

Open:0.6100

Low:0.6005

Close:0.6037

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While acute liver injury is a known risk of Elevidys, this is the first time a death has been reported of anyone taking the therapy. However, Sarepta stated that the patient also had a recent CMV infection, which may have contributed to the outcome, as CMV can damage the liver.Sarepta has reported the event to health authorities, clinical study investigators and prescribing physicians. It intends to update Elevidys’ prescribing information accordingly. Despite the incident, the company maintains that the benefit-risk profile of its gene therapy remains positive, with over 800 patients treated in clinical studies or commercial use.","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/srpt-nosedives-27-patient-death-173800583.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["IE00BFTCPJ56.SGD","BK4007","IE00BJJMRZ35.SGD","RHHBY","BK4585","BK4139","CTMX","IE00BJT1NW94.SGD","IE00B2B36J28.USD","IE0002141913.USD","IE0009355771.USD","SRPT","03165","ANIP"],"gpt_icon":0},{"id":"2520066845","title":"AMGN Posts Upbeat Data on Uplizna From Myasthenia Gravis Study","url":"https://stock-news.laohu8.com/highlight/detail?id=2520066845","media":"Zacks","labels":["dataReport"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2520066845?lang=en_us&edition=fundamental","pubTime":"2025-03-18 00:05","pubTimestamp":1742227500,"startTime":"0","endTime":"0","summary":"Amgen AMGN reported the latest data from the phase III MINT study that evaluated the rare disease drug Uplizna  for label expansion in generalized myasthenia gravis  indication.Data from the study showed that treatment with Uplizna ‘demonstrated durable and sustained efficacy’ in AChR-positive  gMG patients over 52 weeks. These findings were assessed using the Myasthenia Gravis Activities of Daily Living  scores, a patient-reported tool that measures the impact of the disease’s symptoms on a person's ability to perform daily activities. Patients treated with Uplizna for a year showed a 2.8-point improvement over placebo. Per Amgen, about 72% of AChR+ patients in the Uplizna group had an improvement of three or more points in the MG-ADL score compared to 45% in the placebo group.There was also a change in the Quantitative Myasthenia Gravis  score, a physician assessment tool for quantifying disease severity. 69% of AChR+ patients treated with Uplizna showed an improvement of three or mo","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/amgn-posts-upbeat-data-uplizna-160500075.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"dataReport","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BK4139","LU1061106388.HKD","BK4505","IE00B4R5TH58.HKD","LU1983299246.USD","IE00B2B36J28.USD","BK4599","LU1057294990.SGD","ARGX","BK4533","AMGN","BK4581","IE0002141913.USD","IE00BFTCPJ56.SGD","LU2112291526.USD","ANIP","LU0889565916.HKD","BK4566","BK4588","SG9999001440.SGD","BK4585","BK4007","LU1023059063.AUD","LU1571399168.USD","BK4534","LU0289739699.SGD","LU0122379950.USD","LU0320765992.SGD","LU2242646821.SGD","CTMX","LU2242652126.USD","LU0058720904.USD","LU0109394709.USD","IE0009355771.USD","LU0868494617.USD","IE00BJT1NW94.SGD","IE00BJJMRZ35.SGD"],"gpt_icon":0},{"id":"2519015098","title":"Allogene's Q4 Loss Narrower Than Expected, Revenues Nil","url":"https://stock-news.laohu8.com/highlight/detail?id=2519015098","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2519015098?lang=en_us&edition=fundamental","pubTime":"2025-03-14 19:52","pubTimestamp":1741953120,"startTime":"0","endTime":"0","summary":"Allogene Therapeutics ALLO incurred a loss of 28 cents per share in fourth-quarter 2024, narrower than the Zacks Consensus Estimate of a loss of 34 cents. In the year-ago period, the company had incurred a loss of 51 cents per share.See the Zacks Earnings Calendar to stay ahead of market-making news.ALLO did not generate revenues during the reported quarter. The Zacks Consensus Estimate for fourth-quarter sales was pegged at $0.07 million. In the year-ago period, the company recorded revenues of $0.02 million.Year to date, shares of Allogene have lost 11% against the industry’s 6% growth.Research & development (R&D) expenses totaled $45 million, down 18% from the year-ago quarter’s level.General and administrative (G&A) expenses declined 10% year over year to $15.5 million.As of Dec. 31, 2024, Allogene had $373.1 million of cash, cash equivalents and investments, compared with $403.4 million as of Sept. 30, 2024. The company claims that its cash runway will fund operations into the sec","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/allogenes-q4-loss-narrower-expected-115200427.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX","ALLO"],"gpt_icon":0},{"id":"2518677986","title":"CytomX Therapeutics (CTMX) Upgraded to Strong Buy: Here's What You Should Know","url":"https://stock-news.laohu8.com/highlight/detail?id=2518677986","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2518677986?lang=en_us&edition=fundamental","pubTime":"2025-03-12 00:00","pubTimestamp":1741708809,"startTime":"0","endTime":"0","summary":"CytomX Therapeutics  could be a solid choice for investors given its recent upgrade to a Zacks Rank #1 . This upgrade primarily reflects an upward trend in earnings estimates, which is one of the most powerful forces impacting stock prices.The sole determinant of the Zacks rating is a company's changing earnings picture. The Zacks Consensus Estimate -- the consensus of EPS estimates from the sell-side analysts covering the stock -- for the current and following years is tracked by the system.The power of a changing earnings picture in determining near-term stock price movements makes the Zacks rating system highly useful for individual investors, since it can be difficult to make decisions based on rating upgrades by Wall Street analysts. These are mostly driven by subjective factors that are hard to see and measure in real time.As such, the Zacks rating upgrade for CytomX Therapeutics is essentially a positive comment on its earnings outlook that could have a favorable impact on its s","market":"nz","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/cytomx-therapeutics-ctmx-upgraded-strong-160009668.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["CTMX"],"gpt_icon":0}],"pageSize":4,"totalPage":26,"pageCount":1,"totalSize":102}]}}