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Kathryn Haviland; President, Chief Executive Officer, Director; Blueprint Medicines Corp. Christina Rossi; Chief Operating Officer; Blueprint Medicines Corp. Colleen Kusy; Analyst; Robert W. Baird & Co.Good morning. My name is Nadia, and I'll be your conference operator today. At this time, I would like to welcome everyone to the Blueprint Medicines 4Q and FY 2024 earnings release and conference call.Cassie Saitow, you may begin your conference.Thank you, Cassie, and good morning, everyone. At Blueprint Medicines, we are driving growth and innovation with operational excellence. Our aspiration is to fundamentally shift the way allergic and inflammatory diseases are treated by targeting the mast cell.This begins with AYVAKIT, our breakthrough medicine for patients with systemic mastocytosis. In 2024, we delivered $479 million in product revenue, representing impressive annual growth of 135%. AYVAKIT's deep and sustai","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/q4-2024-blueprint-medicines-corp-042308810.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BPMC"],"gpt_icon":0},{"id":"2511507658","title":"Blueprint Medicines: Positive Earnings Call Highlights Growth","url":"https://stock-news.laohu8.com/highlight/detail?id=2511507658","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511507658?lang=en_us&edition=fundamental","pubTime":"2025-02-14 08:35","pubTimestamp":1739493334,"startTime":"0","endTime":"0","summary":"Blueprint Medicines Corp. (($BPMC)) has held its Q4 earnings call. Read on for the main highlights of the call. Blueprint Medicines Corp. recently ...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/company-announcements/blueprint-medicines-positive-earnings-call-highlights-growth?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/company-announcements/blueprint-medicines-positive-earnings-call-highlights-growth?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BPMC"],"gpt_icon":0},{"id":"2511157257","title":"Strong Market Position and Growth Potential Drive Buy Rating for Blueprint Medicines","url":"https://stock-news.laohu8.com/highlight/detail?id=2511157257","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511157257?lang=en_us&edition=fundamental","pubTime":"2025-02-14 04:25","pubTimestamp":1739478343,"startTime":"0","endTime":"0","summary":"TD Cowen analyst Marc Frahm has maintained their bullish stance on BPMC stock, giving a Buy rating today. Marc Frahm has given his Buy rating due t...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/strong-market-position-and-growth-potential-drive-buy-rating-for-blueprint-medicines?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/strong-market-position-and-growth-potential-drive-buy-rating-for-blueprint-medicines?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BPMC"],"gpt_icon":0},{"id":"2511530576","title":"Blueprint Medicines should be bought on any weakness, says Stifel","url":"https://stock-news.laohu8.com/highlight/detail?id=2511530576","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511530576?lang=en_us&edition=fundamental","pubTime":"2025-02-14 02:30","pubTimestamp":1739471408,"startTime":"0","endTime":"0","summary":"Keeping a Buy rating and $155 price target on Blueprint Medicines (BPMC), Stifel says the market is disappointed that 2025 Ayvakit guidance bracket...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-should-be-bought-on-any-weakness-says-stifel?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-should-be-bought-on-any-weakness-says-stifel?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4127","LU0053671581.USD","SF","BPMC","BK4505"],"gpt_icon":0},{"id":"2511576552","title":"Optimistic Growth Potential and Market Expansion Justify Buy Recommendation for Blueprint Medicines","url":"https://stock-news.laohu8.com/highlight/detail?id=2511576552","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511576552?lang=en_us&edition=fundamental","pubTime":"2025-02-14 02:25","pubTimestamp":1739471114,"startTime":"0","endTime":"0","summary":"Bradley Canino, an analyst from Stifel Nicolaus, maintained the Buy rating on Blueprint Medicines (BPMC – Research Report). The associated price ta...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/ratings/optimistic-growth-potential-and-market-expansion-justify-buy-recommendation-for-blueprint-medicines?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/ratings/optimistic-growth-potential-and-market-expansion-justify-buy-recommendation-for-blueprint-medicines?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["LU0053671581.USD","BK4139","BK4505","BPMC"],"gpt_icon":0},{"id":"2511220985","title":"Blueprint Medicines selloff to be short-lived, says Oppenheimer","url":"https://stock-news.laohu8.com/highlight/detail?id=2511220985","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511220985?lang=en_us&edition=fundamental","pubTime":"2025-02-14 00:10","pubTimestamp":1739463008,"startTime":"0","endTime":"0","summary":"Oppenheimer analyst Matthew Biegler says Blueprint Medicines (BPMC) reported Q4 Ayvakit sales of $146M, in line with consensus but below the firm’s...","market":"fut","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-selloff-to-be-short-lived-says-oppenheimer?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":[],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-selloff-to-be-short-lived-says-oppenheimer?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BK4139","BK4505","BK4127","LU0053671581.USD","BPMC","OPY"],"gpt_icon":0},{"id":"2511524967","title":"Wedbush Adjusts Price Target on Blueprint Medicines to $128 From $124, Maintains Outperform Rating","url":"https://stock-news.laohu8.com/highlight/detail?id=2511524967","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511524967?lang=en_us&edition=fundamental","pubTime":"2025-02-13 23:44","pubTimestamp":1739461451,"startTime":"0","endTime":"0","summary":"Blueprint Medicines (BPMC) has an average rating of overweight and mean price target of $128.94, according to analysts polled by FactSet.(MT Newswires covers equity, commodity and economic research fr","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BPMC"],"gpt_icon":0},{"id":"2511529452","title":"Blueprint Medicines Corp reports results for the quarter ended December 31 - Earnings Summary","url":"https://stock-news.laohu8.com/highlight/detail?id=2511529452","media":"Reuters","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511529452?lang=en_us&edition=fundamental","pubTime":"2025-02-13 23:14","pubTimestamp":1739459661,"startTime":"0","endTime":"0","summary":"Blueprint Medicines Corp reports results for the quarter ended December 31 - Earnings SummaryBlueprint Medicines Corp BPMC.OQ reported a quarterly adjusted loss of 79 cents per share for the quarter e","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://api.refinitiv.com/data/news/v1/stories/urn:newsml:reuters.com:20250213:nL8N3P4247:1","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BPMC"],"gpt_icon":0},{"id":"1140978482","title":"Stock Track | Blueprint Medicines Plummets 8.27% as Q4 Earnings Miss Overshadows Revenue Beat","url":"https://stock-news.laohu8.com/highlight/detail?id=1140978482","media":"Stock Track","labels":["movement"],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/1140978482?lang=en_us&edition=fundamental","pubTime":"2025-02-13 22:37","pubTimestamp":1739457447,"startTime":"0","endTime":"0","summary":"Blueprint Medicines Corp.  saw its stock plummet 8.27% in pre-market trading on Thursday, after the company reported its fourth-quarter and full-year 2024 financial results.The biopharmaceutical company, focused on developing treatments for cancer and rare diseases, reported mixed results for the quarter:. Earnings: Q4 GAAP EPS of $ missed the analyst consensus estimate of $ by 12.86%.Revenue: Q4 revenue of $146.37 million beat the analyst consensus estimate of $145.84 million by 0.36%. This rep","market":"hk","thumbnail":"","type":0,"news_type":0,"thumbnails":[],"rights":null,"property":[],"language":"en","translate_title":"","themeId":"","theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"movement","news_rank":0,"length":0,"strategy_id":0,"source":"ai_movement_en","symbols":["BPMC"],"gpt_icon":0},{"id":"2511523661","title":"Blueprint Medicines Price Target Maintained With a $133.00/Share by Needham","url":"https://stock-news.laohu8.com/highlight/detail?id=2511523661","media":"Dow Jones","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511523661?lang=en_us&edition=fundamental","pubTime":"2025-02-13 22:00","pubTimestamp":1739455200,"startTime":"0","endTime":"0","summary":"Ratings actions from Benzinga: https://www.benzinga.com/quote/BPMC/analyst-ratings \n\n\n \n\n\n  (END) Dow Jones Newswires\n\n\n  February 13, 2025 09:00 ET (14:00 GMT)","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["rate"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://dowjonesnews.com/newdjn/logon.aspx?AL=N","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":null,"symbols":["BPMC"],"gpt_icon":0},{"id":"2511297455","title":"Blueprint Medicines (BPMC) Reports Q4 Loss, Misses Revenue Estimates","url":"https://stock-news.laohu8.com/highlight/detail?id=2511297455","media":"Zacks","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511297455?lang=en_us&edition=fundamental","pubTime":"2025-02-13 21:25","pubTimestamp":1739453106,"startTime":"0","endTime":"0","summary":"Blueprint Medicines  came out with a quarterly loss of $0.79 per share versus the Zacks Consensus Estimate of a loss of $0.70. This compares to loss of $1.82 per share a year ago. These figures are adjusted for non-recurring items.This quarterly report represents an earnings surprise of -12.86%. A quarter ago, it was expected that this cancer drug developer would post a loss of $0.97 per share when it actually produced a loss of $0.89, delivering a surprise of 8.25%.Blueprint Medicines , which belongs to the Zacks Medical - Biomedical and Genetics industry, posted revenues of $146.37 million for the quarter ended December 2024, missing the Zacks Consensus Estimate by 0.79%. This compares to year-ago revenues of $71.96 million. The company has topped consensus revenue estimates three times over the last four quarters.Blueprint Medicines shares have added about 18.7% since the beginning of the year versus the S&P 500's gain of 2.9%.While Blueprint Medicines has outperformed the market so","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/blueprint-medicines-bpmc-reports-q4-132506688.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BPMC"],"gpt_icon":0},{"id":"2511547250","title":"Blueprint Medicines Q4 Loss Narrows, Revenue Rises","url":"https://stock-news.laohu8.com/highlight/detail?id=2511547250","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511547250?lang=en_us&edition=fundamental","pubTime":"2025-02-13 21:24","pubTimestamp":1739453072,"startTime":"0","endTime":"0","summary":"Blueprint Medicines  reported a Q4 net loss Thursday of $0.79 per diluted share, narrowing from a loss of $1.82 a year earlier.Analysts polled by FactSet expected a loss of $0.67.Revenue for the quarter ended Dec. 31, 2024, was $146.4 million, up from $72 million a year earlier.Analysts surveyed by FactSet expected $146 million.The company's shares were down nearly 9% in recent Thursday premarket activity.Price: 94.50, Change: -9.06, Percent Change: -8.8","market":"hk","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BPMC"],"gpt_icon":0},{"id":"2511106544","title":"Earnings Flash (BPMC) Blueprint Medicines Posts Q4 Net Loss $-0.79 a Share, vs. FactSet Est of $-0.67 Loss","url":"https://stock-news.laohu8.com/highlight/detail?id=2511106544","media":"MT Newswires Live","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511106544?lang=en_us&edition=fundamental","pubTime":"2025-02-13 20:46","pubTimestamp":1739450780,"startTime":"0","endTime":"0","summary":"Earnings Flash (BPMC) Blueprint Medicines Posts Q4 Net Loss $-0.79 a Share, vs. FactSet Est of $-0.67 Loss","market":"sg","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.mtnewswires.com/","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"-1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"mtnewswires_news","symbols":["BPMC"],"gpt_icon":0},{"id":"2511544558","title":"Blueprint Medicines: Q4 Earnings Snapshot","url":"https://stock-news.laohu8.com/highlight/detail?id=2511544558","media":"Associated Press Finance","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511544558?lang=en_us&edition=fundamental","pubTime":"2025-02-13 20:21","pubTimestamp":1739449308,"startTime":"0","endTime":"0","summary":"CAMBRIDGE, Mass.  — CAMBRIDGE, Mass.  — Blueprint Medicines Corp.  on Thursday reported a loss of $50 million in its fourth quarter.On a per-share basis, the Cambridge, Massachusetts-based company said it had a loss of 79 cents.The results fell short of Wall Street expectations. The average estimate of 10 analysts surveyed by Zacks Investment Research was for a loss of 70 cents per share.The cancer drug developer posted revenue of $146.4 million in the period, which also missed Street forecasts. Ten analysts surveyed by Zacks expected $147.5 million.For the year, the company reported that its loss narrowed to $67.1 million, or $1.07 per share. Revenue was reported as $508.8 million.Blueprint Medicines shares have risen 19% since the beginning of the year. The stock has increased 34% in the last 12 months.","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":null,"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://finance.yahoo.com/news/blueprint-medicines-q4-earnings-snapshot-122148936.html","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"0","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"yahoofinance","symbols":["BPMC"],"gpt_icon":0},{"id":"2511419135","title":"Blueprint Medicines reports Q4 EPS (79c), consensus (71c)","url":"https://stock-news.laohu8.com/highlight/detail?id=2511419135","media":"TIPRANKS","labels":[],"top":-1,"itemType":null,"share":"https://ttm.financial/m/news/2511419135?lang=en_us&edition=fundamental","pubTime":"2025-02-13 20:21","pubTimestamp":1739449269,"startTime":"0","endTime":"0","summary":"Reports Q4 revenue $144.1M, consensus $145.18M. “We are entering 2025 in the strongest position we have ever been in as a company with a focus on d...","market":"us","thumbnail":null,"type":0,"news_type":0,"thumbnails":[],"rights":{"source":"tipranks_highlight","url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-reports-q4-eps-79c-consensus-71c?utm_source=itigerup.com&utm_medium=referral","rn_cache_url":null,"directOrigin":true},"property":["earning"],"language":"en","translate_title":"","themeId":null,"theme_name":"","theme_type":"","isJumpTheme":false,"source_url":"https://www.tipranks.com/news/the-fly/blueprint-medicines-reports-q4-eps-79c-consensus-71c?utm_source=itigerup.com&utm_medium=referral","is_publish_highlight":false,"source_rank":0,"column":"","sentiment":"1","news_top_title":null,"news_tag":"","news_rank":0,"length":0,"strategy_id":0,"source":"tipranks_highlight","symbols":["BPMC"],"gpt_icon":0}],"pageSize":16,"totalPage":9,"pageCount":2,"totalSize":130}]}}